Evidence map›Paper›PMID 30012112›Full record

ArticleBMC infectious diseases2018

Maternal and infant death after probable vertical transmission of chikungunya virus in Brazil - case report.

Rhaquel de Morais Alves Barbosa Oliveira, Francisca Kalline de Almeida Barreto, Ana Maria Peixoto Cabral Maia, Ileana Pitombeira Gomes, Adriana Rocha Simião, Rebeca Bandeira Barbosa, Adilina Soares Romeiro Rodrigues, Kilma Wanderley Lopes, Fernanda Montenegro de Carvalho Araújo, Regina Lúcia Sousa do Vale and 2 more

Abstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Current Status of Chikungunya in India.Frontiers in microbiology · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rhaquel de Morais Alves Barbosa OliveiraCollective Health, Federal University of Ceara (UFC), Fortaleza, CE, Brazil.
Francisca Kalline de Almeida BarretoCollective Health, Federal University of Ceara (UFC), Fortaleza, CE, Brazil.
Ana Maria Peixoto Cabral MaiaCollective Health, Federal University of Ceara (UFC), Fortaleza, CE, Brazil.
Ileana Pitombeira GomesCollective Health, Federal University of Ceara (UFC), Fortaleza, CE, Brazil.
Adriana Rocha SimiãoCollective Health, Federal University of Ceara (UFC), Fortaleza, CE, Brazil.
Rebeca Bandeira BarbosaCollective Health, Federal University of Ceara (UFC), Fortaleza, CE, Brazil.
Adilina Soares Romeiro RodriguesCollective Health, Federal University of Ceara (UFC), Fortaleza, CE, Brazil.
Kilma Wanderley LopesMember of the Investigation Committee for arbovirus deaths, Fortaleza, CE, Brazil.
Fernanda Montenegro de Carvalho AraújoMember of the Investigation Committee for arbovirus deaths, Fortaleza, CE, Brazil.
Regina Lúcia Sousa do ValeMember of the Investigation Committee for arbovirus deaths, Fortaleza, CE, Brazil.
John Washington CavalcantePathology, Federal University of Ceara (UFC), Fortaleza, CE, Brazil.
Luciano Pamplona de Góes CavalcantiMember of the Investigation Committee for arbovirus deaths, Fortaleza, CE, Brazil. pamplona.luciano@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChikungunya virus infection in neonates is relatively rare and can lead to death. CASE PRESENTATION: We report the occurrence of the first death of a mother and child after probable vertical transmission of chikungunya virus in Brazil. A 28-year-old pregnant woman with hypertension presented with symptoms compatible with an arboviral disease at 34 weeks' gestation. She developed preeclampsia with severe respiratory failure which resulted in the emergency cesarean section, and the patient died 12 days after the onset of symptoms. The pre-term newborn weighed 2535 g, with an Apgar score of 4/8. He was referred to the neonatal ICU with neutrophilia and thrombocytopenia, several seizure episodes, and hemorrhagic disorders, which resulted in death. Chikungunya IgM antibody was detected in the cerebrospinal fluid.

conclusionsWe present the first documented maternal and neonatal death in Brazil after probable chikungunya infection during pregnancy.

Indexed as

Infectious Disease Transmission, VerticalAdultBrazilCesarean SectionChikungunya FeverChikungunya virusFatal OutcomeFemaleGestational AgeHumansInfant, NewbornMalePerinatal DeathPre-EclampsiaPregnancyPregnancy Complications, InfectiousArbovirus infectionChikungunya virusDeathsVertical transmission

Identifiers

PMID30012112
PMCPMC6048842

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.