Evidence map›Paper›PMID 30011971›Full record

ArticleViruses2018

Conserved Active-Site Residues Associated with OAS Enzyme Activity and Ubiquitin-Like Domains Are Not Required for the Antiviral Activity of goOASL Protein against Avian Tembusu Virus.

Shun Chen, Chao Yang, Jinyue Zhang, Zhen Wu, Mingshu Wang, Renyong Jia, Dekang Zhu, Mafeng Liu, Qiao Yang, Ying Wu and 7 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Functional Analysis of Oligoadenylate Synthetase in the Emu (Animals : an open access journal from MDPI · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Shun ChenInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. shunchen@sicau.edu.cn.ORCID 0000-0002-7488-1037
Chao YangInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. 15108224618@163.com.
Jinyue ZhangInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. zhangjinyue@sicau.cn.
Zhen WuInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. wu_zhen666@outlook.com.
Mingshu WangInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. mshwang@163.com.
Renyong JiaInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. cqrc_jry@163.com.
Dekang ZhuResearch Center of Avian Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. zdk24@sicau.edu.cn.ORCID 0000-0002-7314-1088
Mafeng LiuInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. liumafengra@163.com.
Qiao YangInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yangqiao721521@sina.com.
Ying WuInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yingzi_no1@126.com.
Xinxin ZhaoInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. xxinzhao@sicau.edu.cn.
Shaqiu ZhangInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. shaqiu86@hotmail.com.
Yunya LiuInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yunnyaaliu@163.com.
Ling ZhangInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. zl97451@126.com.
Yanling YuInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. yanling3525@163.com.
Yu YouInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. youyu3508@gmail.com.
Anchun ChengInstitute of Preventive Veterinary Medicine, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. chenganchun@vip.163.com.ORCID 0000-0001-6093-353X
Sichuan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon (IFN)-induced 2'-5'-oligoadenylate synthetase (OAS) proteins exhibit an extensive and efficient antiviral effect against flavivirus infection in mammals and birds. Only the 2'-5'-oligoadenylate synthetase-like (

Indexed as

Flavivirus2',5'-Oligoadenylate SynthetaseAnimalsBird DiseasesCatalytic DomainCells, CulturedDucksFibroblastsFlavivirus InfectionsGeeseMutationPlasmidsTransfectionUbiquitin2',5'-Oligoadenylate SynthetaseUbiquitin2′-5′-oligoadenylate synthetase enzyme activity2′-5′-oligoadenylate synthetase-likeantiviral activityduck-origin Tembusu virusgooseubiquitin-like domains

Identifiers

PMID30011971
PMCPMC6071104
OpenAlexW2883261982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.