Evidence map›Paper›PMID 30011929›Full record

ArticleMolecules (Basel, Switzerland)2018

Construction of Thermo-Responsive Elastin-Like Polypeptides (ELPs)-Aggregation-Induced-Emission (AIE) Conjugates for Temperature Sensing.

Zhe Chen, Zhaoyang Ding, Guangya Zhang, Leilei Tian, Xuanjun Zhang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhe ChenFaculty of Health Sciences, University of Macau, Taipa 999078, Macau, China. yb67616@umac.mo.
Zhaoyang DingFaculty of Health Sciences, University of Macau, Taipa 999078, Macau, China. zyding1@uw.edu.ORCID 0000-0003-4657-992X
Guangya ZhangDepartment of Biotechnology and Bioengineering, Huaqiao University, Xiamen 361021, China. zhgyghh@hqu.edu.cn.
Leilei TianDepartment of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China. tianll@sustc.edu.cn.
Xuanjun ZhangFaculty of Health Sciences, University of Macau, Taipa 999078, Macau, China. xuanjunzhang@umac.mo.ORCID 0000-0001-6452-1778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, an aggregation-induced emission (AIE) molecule (tetraphenylethene derivative, TPE-COOH) was conjugated to elastin-like polypeptides (ELPs40) via an amide bond to form ELPs40-TPE. The successful synthesis of ELPs40-TPE was confirmed by Circular Dichroism spectroscopy, gel electrophoresis, UV-vis absorption, and fluorescence emission spectroscopy. ELPs40-TPE possessed both amphiphilicity and the features of an AIE, and the fluorescence intensity was dependent on the local temperature. The Hela cells imaging indicated that ELPs40-TPE has great potential for bio-imaging applications because of its advantages of high fluorescence intensity, good water-solubility, and remarkable biocompatibility.

Indexed as

ElastinFluorescenceTemperatureHeLa CellsHumansElastinaggregation-induced-emission (AIE)elastin-like polypeptides (ELPs)temperature sensingthermo-responsive

Identifiers

PMID30011929
PMCPMC6100176

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.