Evidence map›Paper›PMID 30011926›Full record

ArticleInternational journal of molecular sciences2018

Engineering Cell Adhesion and Orientation via Ultrafast Laser Fabricated Microstructured Substrates.

Eleftheria Babaliari, Paraskevi Kavatzikidou, Despoina Angelaki, Lefki Chaniotaki, Alexandra Manousaki, Alexandra Siakouli-Galanopoulou, Anthi Ranella, Emmanuel Stratakis

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Microfluidic Systems for Neural Cell Studies.Bioengineering (Basel, Switzerland) · 2023
    Review
  5. Article
  6. Article
  7. Review
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  9. Article
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  13. Review
  14. Novel Biomaterials for Tissue Engineering 2018.International journal of molecular sciences · 2018
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Eleftheria BabaliariFoundation for Research and Technology-Hellas (F.O.R.T.H.), Institute of Electronic Structure and Laser (I.E.S.L.), Vassilika Vouton, 711 10 Heraklion, Greece. ebabaliari@iesl.forth.gr.
Paraskevi KavatzikidouFoundation for Research and Technology-Hellas (F.O.R.T.H.), Institute of Electronic Structure and Laser (I.E.S.L.), Vassilika Vouton, 711 10 Heraklion, Greece. ekavatzi@iesl.forth.gr.
Despoina AngelakiFoundation for Research and Technology-Hellas (F.O.R.T.H.), Institute of Electronic Structure and Laser (I.E.S.L.), Vassilika Vouton, 711 10 Heraklion, Greece. angelaki@iesl.forth.gr.
Lefki ChaniotakiDepartment of Materials Science and Technology, University of Crete, 70013 Crete, Greece. mst1095@edu.materials.uoc.gr.
Alexandra ManousakiFoundation for Research and Technology-Hellas (F.O.R.T.H.), Institute of Electronic Structure and Laser (I.E.S.L.), Vassilika Vouton, 711 10 Heraklion, Greece. manousa@iesl.forth.gr.
Alexandra Siakouli-GalanopoulouDepartment of Biology, University of Crete, 70013 Crete, Greece. siakouli@biology.uoc.gr.
Anthi RanellaFoundation for Research and Technology-Hellas (F.O.R.T.H.), Institute of Electronic Structure and Laser (I.E.S.L.), Vassilika Vouton, 711 10 Heraklion, Greece. ranthi@iesl.forth.gr.
Emmanuel StratakisFoundation for Research and Technology-Hellas (F.O.R.T.H.), Institute of Electronic Structure and Laser (I.E.S.L.), Vassilika Vouton, 711 10 Heraklion, Greece. stratak@iesl.forth.gr.ORCID 0000-0002-1908-8618
University of Crete · GRFORTH Institute of Electronic Structure and Laser · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell responses depend on the stimuli received by the surrounding extracellular environment, which provides the cues required for adhesion, orientation, proliferation, and differentiation at the micro and the nano scales. In this study, discontinuous microcones on silicon (Si) and continuous microgrooves on polyethylene terephthalate (PET) substrates were fabricated via ultrashort pulsed laser irradiation at various fluences, resulting in microstructures with different magnitudes of roughness and varying geometrical characteristics. The topographical models attained were specifically developed to imitate the guidance and alignment of Schwann cells for the oriented axonal regrowth that occurs in nerve regeneration. At the same time, positive replicas of the silicon microstructures were successfully reproduced via soft lithography on the biodegradable polymer poly(lactide-

Indexed as

AnimalsAxonsBiocompatible MaterialsCell AdhesionCell DifferentiationCell LineLactic AcidLasersMiceNerve RegenerationPolyethylene TerephthalatesPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerSchwann CellsSiliconSurface PropertiesBiocompatible MaterialsLactic AcidPolyethylene TerephthalatesPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerSiliconcell adhesioncell orientationlaser fabricationpolymeric materialsSchwann cellssoft lithographytopography

Identifiers

PMID30011926
PMCPMC6073590
OpenAlexW2809767602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.