Evidence map›Paper›PMID 30011893›Full record

ArticleMolecules (Basel, Switzerland)2018

Application of Spray Drying Particle Engineering to a High-Functionality/Low-Solubility Milk Thistle Extract: Powders Production and Characterization.

Francesca Sansone, Tiziana Esposito, Maria Rosaria Lauro, Patrizia Picerno, Teresa Mencherini, Franco Gasparri, Stefania De Santis, Marcello Chieppa, Claudia Cirillo, Rita Patrizia Aquino

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Study onPharmaceutics · 2020
    Article
  3. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Francesca SansoneDepartment of Pharmacy, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy. fsansone@unisa.it.
Tiziana EspositoDepartment of Pharmacy, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy. tesposito@unisa.it.
Maria Rosaria LauroDepartment of Pharmacy, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy. lauro@unisa.it.ORCID 0000-0001-7362-826X
Patrizia PicernoDepartment of Pharmacy, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy. ppicerno@unisa.it.
Teresa MencheriniDepartment of Pharmacy, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy. tmencherini@unisa.it.ORCID 0000-0001-8207-0085
Franco GasparriDepartment of Pharmacy, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy. info@gasparrifranco.it.
Stefania De SantisIRCCS "de Bellis", Laboratory of Experimental Immunopathology, 70013 Castellana Grotte, Italy. s-desantis@live.it.
Marcello ChieppaPhD Program in Drug Discovery and Development, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy. mchieppa@unisa.it.
Claudia CirilloDepartment of Industrial Engineering and NANO_MATES Research Centre, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy. clcirillo@unisa.it.
Rita Patrizia AquinoDepartment of Pharmacy, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy. aquinorp@unisa.it.
University of Salerno · ITGastroenterology Hospital "Saverio de Bellis" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many natural compounds having antioxidant and anti-inflammatory activity are a potential target for new therapies against chronic inflammatory syndromes. The oral administration of functional herbal supplements may become a prevention strategy or therapy adjuvant for susceptible patients. A case study is our milk thistle (

Indexed as

Carboxymethylcellulose SodiumPlant ExtractsSilymarinAnimalsDendritic CellsMicePowdersSilybum marianumCarboxymethylcellulose SodiumPlant ExtractsPowdersSilymarinanti-inflammatory activityfunctional stabilityin vitro dissolution and permeation testssilymarin complexwater solubility

Identifiers

PMID30011893
PMCPMC6100597
OpenAlexW2884914249

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.