Convenient Method of Synthesizing Aryloxyalkyl Esters from Phenolic Esters Using Halogenated Alcohols.

Xueyang Jiang, Junting Zhou, Yue Zhou, Haopeng Sun, Jian Xu, Feng Feng, Wei Qu

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Synthesis and Evaluation of NovelACS medicinal chemistry letters · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xueyang JiangDepartment of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. ajyang@stu.cpu.edu.cn.ORCID 0000-0003-0135-5615

Junting ZhouDepartment of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. zhoujunting0920@163.com.

Yue ZhouDepartment of Pharmacy Administration & Clinical Pharmacy, Peking University, Beijing 100191, China. yuezhouzhy@163.com.ORCID 0000-0002-7797-4001

Haopeng SunDepartment of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. sunhaopeng@163.com.

Jian XuDepartment of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. xujian201009@126.com.

Feng FengDepartment of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. fengfeng@cpu.edu.cn.

Wei QuDepartment of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. popoqzh@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A facile one-pot synthetic method of building aryloxyalkyl esters was developed using various types of phenolic esters with halogenated alcohols. The ready availability of both starting materials, coupled with the required simple experimental technique, enables the current synthetic method of producing aryloxyalkyl esters in a fast and efficient way. It is noteworthy that acyl transfer was demonstrated in this reaction.

Indexed as

AlcoholsEstersHydrocarbons, HalogenatedHydroxybenzoatesAlcoholsEstersHydrocarbons, HalogenatedHydroxybenzoatesphenolic acidacyl transferaryloxyalkyl estersphenolic esters

Identifiers

PMID30011871

DOI10.3390/molecules23071715

PMCPMC6100006

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.