Evidence map›Paper›PMID 30011852›Full record

ArticleInternational journal of molecular sciences2018

PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration.

Gabriele Dammone, Sonia Karaz, Laura Lukjanenko, Carine Winkler, Federico Sizzano, Guillaume Jacot, Eugenia Migliavacca, Alessio Palini, Béatrice Desvergne, Federica Gilardi and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 66 citations in OpenAlex.

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  18. Cardiac macrophage metabolism in health and disease.Trends in endocrinology and metabolism: TEM · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Gabriele DammoneNestle Institute of Health Sciences, EPFL Innovation Park, Building H, EPFL Campus, 1015 Lausanne, Switzerland. gabriele.dammone@rd.nestle.com.
Sonia KarazNestle Institute of Health Sciences, EPFL Innovation Park, Building H, EPFL Campus, 1015 Lausanne, Switzerland. sonia.karaz@rd.nestle.com.
Laura LukjanenkoNestle Institute of Health Sciences, EPFL Innovation Park, Building H, EPFL Campus, 1015 Lausanne, Switzerland. laura.lukjanenko@rd.nestle.com.
Carine WinklerCenter for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, 1015 Lausanne, Switzerland. carine.winkler@unil.ch.
Federico SizzanoNestle Institute of Health Sciences, EPFL Innovation Park, Building H, EPFL Campus, 1015 Lausanne, Switzerland. federico.sizzano@rd.nestle.com.
Guillaume JacotNestle Institute of Health Sciences, EPFL Innovation Park, Building H, EPFL Campus, 1015 Lausanne, Switzerland. guillaume.jacot@rd.nestle.com.
Eugenia MigliavaccaNestle Institute of Health Sciences, EPFL Innovation Park, Building H, EPFL Campus, 1015 Lausanne, Switzerland. eugenia.migliavacca@rd.nestle.com.
Alessio PaliniNestle Institute of Health Sciences, EPFL Innovation Park, Building H, EPFL Campus, 1015 Lausanne, Switzerland. alessio.palini@rd.nestle.com.
Béatrice DesvergneCenter for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, 1015 Lausanne, Switzerland. beatrice.desvergne@unil.ch.
Federica GilardiCenter for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, 1015 Lausanne, Switzerland. Federica.Gilardi@hcuge.ch.
Jerome N FeigeNestle Institute of Health Sciences, EPFL Innovation Park, Building H, EPFL Campus, 1015 Lausanne, Switzerland. Jerome.Feige@rd.nestle.com.ORCID 0000-0002-4751-264X
École Polytechnique Fédérale de Lausanne · CHUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skeletal muscle is a regenerative tissue which can repair damaged myofibers through the activation of tissue-resident muscle stem cells (MuSCs). Many muscle diseases with impaired regeneration cause excessive adipose tissue accumulation in muscle, alter the myogenic fate of MuSCs, and deregulate the cross-talk between MuSCs and fibro/adipogenic progenitors (FAPs), a bi-potent cell population which supports myogenesis and controls intra-muscular fibrosis and adipocyte formation. In order to better characterize the interaction between adipogenesis and myogenesis, we studied muscle regeneration and MuSC function in whole body

Indexed as

AdipocytesAdipogenesisAnimalsCell DifferentiationCells, CulturedFemaleGene Expression Regulation, DevelopmentalMaleMice, KnockoutMice, TransgenicMuscle DevelopmentMuscle, SkeletalMyoblastsPPAR gammaRegenerationPPAR gammaadipogenesisinflammationmuscle stem cellsmyogenesisPPARgregenerationsatellite cellsSkeletal muscle

Identifiers

PMID30011852
PMCPMC6073847
OpenAlexW2884925377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.