Evidence map›Paper›PMID 30011807›Full record

ReviewBiosensors2018

Autoantibodies as Potential Biomarkers in Breast Cancer.

Jingyi Qiu, Bailey Keyser, Zuan-Tao Lin, Tianfu Wu

Abstract readReview
In one paragraph

Review in Biosensors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Trial
  4. The early diagnostic value of lung cancer autoantibodies and tumor markers in lung cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jingyi QiuDepartment of Biomedical Engineering, University of Houston, 3517 Cullen BLVD, SERC 2008, Houston, TX 77204, USA. yva1ne@hotmail.com.
Bailey KeyserDepartment of Biomedical Engineering, University of Houston, 3517 Cullen BLVD, SERC 2008, Houston, TX 77204, USA. bbkeyser@central.uh.edu.
Zuan-Tao LinDepartment of Biomedical Engineering, University of Houston, 3517 Cullen BLVD, SERC 2008, Houston, TX 77204, USA. zuantaolin@gmail.com.
Tianfu WuDepartment of Biomedical Engineering, University of Houston, 3517 Cullen BLVD, SERC 2008, Houston, TX 77204, USA. twu13@central.uh.edu.ORCID 0000-0003-4406-1449

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is a major cause of mortality in women; however, technologies for early stage screening and diagnosis (e.g., mammography and other imaging technologies) are not optimal for the accurate detection of cancer. This creates demand for a more effective diagnostic means to replace or be complementary to existing technologies for early discovery of breast cancer. Cancer neoantigens could reflect tumorigenesis, but they are hardly detectable at the early stage. Autoantibodies, however, are biologically amplified and hence may be measurable early on, making them promising biomarkers to discriminate breast cancer from healthy tissue accurately. In this review, we summarized the recent findings of breast cancer specific antigens and autoantibodies, which may be useful in early detection, disease stratification, and monitoring of treatment responses of breast cancer.

Indexed as

AutoantibodiesBiomarkers, TumorBiosensing TechniquesBreast NeoplasmsEarly Detection of CancerFemaleHumansImmunoassayProteomeAutoantibodiesBiomarkers, TumorProteomeautoantibodybreast cancerearly diagnosisimmunotherapy

Identifiers

PMID30011807
PMCPMC6163859

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.