Trial reportThe journals of gerontology. Series A, Biological sciences and medical sciences2019
Translating the Lifestyle Interventions and Independence for Elders Clinical Trial to Older Adults in a Real-World Community-Based Setting.
Trial report in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03750682 (ENhancing Independence Using Group-Based Community Interventions for Healthy AGing Elders), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
ENhancing Independence Using Group-Based Community Interventions for Healthy AGing Elders: The ENGAGE for Brain Health Pilot Study
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Community-based interventions to support aging in place and functional independence in older adults: a systematic review of randomized controlled trials.Frontiers in public health · 2026Pooled it
- Interventions to Improve Depressive Symptoms in Community-Dwelling Older Adults: A Scoping Review.Journal of prevention (2022) · 2026Article
- Outcomes During a One-Year Multidisciplinary Lifestyle Program in Japanese Specialty Care: A Retrospective Observational Study.Pragmatic and observational research · 2026Article
- Keep it Movin': Design and methods of a church-based physical activity program to improve physical function among midlife and older black adults.Contemporary clinical trials · 2024Article
- "You Just Have to Keep It Movin':" Perceptions of Physical Function Limitations in an African American Health Ministry.Journal of racial and ethnic health disparities · 2024Article
- A feasibility randomized controlled trial of a community-level physical activity strategy for older adults with motoric cognitive risk syndrome.Frontiers in aging · 2024Article
- Exercise based reduction of falls in communitydwelling older adults: a network meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023Review
- Association between Pre-Intervention Physical Activity Level and Treatment Response to Exercise Therapy in Persons with Knee Osteoarthritis - An Exploratory Study.ACR open rheumatology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
backgroundThe Lifestyle Interventions and Independence for Elders (LIFE) clinical trial demonstrated that a structured program of physical activity (PA) reduced mobility-disability in older adults by up to 28%. It remains unknown whether the benefits of LIFE PA can be translated to older adults at risk for mobility-disability in real-world community-based settings. To address this knowledge gap, we conducted the ENhancing independence using Group-based community interventions for healthy AGing in Elders (ENGAGE) pilot study and examined the safety, feasibility, and preliminary effectiveness of translating LIFE PA to a community-based senior center.
methodsForty older adults with severe lower extremity functional limitations (age: 76.9 ± 7.3 years; body mass index: 32.7 ± 8 kg/m2; 85% female; short physical performance battery score: 6.3 ± 2.2) were randomized to 24 weeks of PA or a health education control intervention.
resultsCommunity-based PA was safe (serious adverse events: PA vs health education, 0:2; nonserious adverse events: PA vs health education, 3:1) and participants successfully adhered to the PA intervention (65.2%). Compared to health education, PA participants who attended ≥25% of scheduled visits had meaningful and sustained short physical performance battery improvements at follow-up (between group short physical performance battery score differences: ~0.7 units).
conclusionsENGAGE has demonstrated the preliminary safety, feasibility, and effectiveness of LIFE PA in a real-world community-based setting. Larger-scale translational studies are needed to further disseminate the benefits of LIFE PA to vulnerable older adults in a variety of community-based settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.