Evidence map›Paper›PMID 30010749›Full record

ArticleDatabase : the journal of biological databases and curation2018

Improving the learning of chemical-protein interactions from literature using transfer learning and specialized word embeddings.

P Corbett, J Boyle

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Prompt Tuning in Biomedical Relation Extraction.Journal of healthcare informatics research · 2024
    Article
  2. Review
  3. Extraction of causal relations based on SBEL and BERT model.Database : the journal of biological databases and curation · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

P CorbettData Science Group, Technology Department, The Royal Society of Chemistry, Thomas Graham House (290), Science Park, Milton Road, Cambridge CB4 0WF, UK.
J BoyleData Science Group, Technology Department, The Royal Society of Chemistry, Thomas Graham House (290), Science Park, Milton Road, Cambridge CB4 0WF, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this paper, we explore the application of artificial neural network ('deep learning') methods to the problem of detecting chemical-protein interactions in PubMed abstracts. We present here a system using multiple Long Short Term Memory layers to analyse candidate interactions, to determine whether there is a relation and which type. A particular feature of our system is the use of unlabelled data, both to pre-train word embeddings and also pre-train LSTM layers in the neural network. On the BioCreative VI CHEMPROT test corpus, our system achieves an F score of 61.51% (56.10% precision, 67.84% recall).

Indexed as

AlgorithmsDatabases, ChemicalPublicationsNeural Networks, ComputerProteinsProteins

Identifiers

PMID30010749
PMCPMC6044291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.