Evidence map›Paper›PMID 30010731›Full record

ArticleDatabase : the journal of biological databases and curation2018

Leveraging prior knowledge for protein-protein interaction extraction with memory network.

Huiwei Zhou, Zhuang Liu, Shixian Ning, Yunlong Yang, Chengkun Lang, Yingyu Lin, Kun Ma

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huiwei ZhouSchool of Computer Science and Technology, Dalian University of Technology, Chuangxinyuan Building, No. 2 Linggong Road, Ganjingzi District, Dalian, Liaoning, China.
Zhuang LiuSchool of Computer Science and Technology, Dalian University of Technology, Chuangxinyuan Building, No. 2 Linggong Road, Ganjingzi District, Dalian, Liaoning, China.
Shixian NingSchool of Computer Science and Technology, Dalian University of Technology, Chuangxinyuan Building, No. 2 Linggong Road, Ganjingzi District, Dalian, Liaoning, China.
Yunlong YangSchool of Computer Science and Technology, Dalian University of Technology, Chuangxinyuan Building, No. 2 Linggong Road, Ganjingzi District, Dalian, Liaoning, China.
Chengkun LangSchool of Computer Science and Technology, Dalian University of Technology, Chuangxinyuan Building, No. 2 Linggong Road, Ganjingzi District, Dalian, Liaoning, China.
Yingyu LinSchool of Foreign Languages, Dalian University of Technology, Arts Building, No. 2 Linggong Road, Ganjingzi District, Dalian, Liaoning, China.
Kun MaSchool of Life Science and Medicine, Dalian University of Technology, F03 Building, No. 2 Dagong Road, Liaodongwan District, Panjin, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Automatically extracting protein-protein interactions (PPIs) from biomedical literature provides additional support for precision medicine efforts. This paper proposes a novel memory network-based model (MNM) for PPI extraction, which leverages prior knowledge about protein-protein pairs with memory networks. The proposed MNM captures important context clues related to knowledge representations learned from knowledge bases. Both entity embeddings and relation embeddings of prior knowledge are effective in improving the PPI extraction model, leading to a new state-of-the-art performance on the BioCreative VI PPI dataset. The paper also shows that multiple computational layers over an external memory are superior to long short-term memory networks with the local memories.Database URL: http://www.biocreative.org/tasks/biocreative-vi/track-4/.

Indexed as

KnowledgeNeural Networks, ComputerProtein Interaction MappingAlgorithmsDatabases, ProteinStatistics as Topic

Identifiers

PMID30010731
PMCPMC6047414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.