ArticleBriefings in bioinformatics2019
A comprehensive survey of models for dissecting local ancestry deconvolution in human genome.
Article in Briefings in bioinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Establishing Best Practices for Clinical GWAS: Tackling Imputation and Data Quality Challenges.International journal of molecular sciences · 2025Review
- Recomb-Mix: fast and accurate local ancestry inference.Bioinformatics (Oxford, England) · 2025Article
- Ancient dog introgression into the Iberian wolf genome may have facilitated adaptation to human-dominated landscapes.Genome research · 2025Article
- Enabling efficient analysis of biobank-scale data with genotype representation graphs.Nature computational science · 2025Article
- Fast and accurate local ancestry inference with Recomb-Mix.bioRxiv : the preprint server for biology · 2024Article
- Swordtail fish hybrids reveal that genome evolution is surprisingly predictable after initial hybridization.PLoS biology · 2024Article
- Genome evolution is surprisingly predictable after initial hybridization.bioRxiv : the preprint server for biology · 2023Article
- Strategies for the Genomic Analysis of Admixed Populations.Annual review of biomedical data science · 2023Review
- Genome-Wide Admixture Mapping Identifies Wild Ancestry-of-Origin Segments in Cultivated Robusta Coffee.Genome biology and evolution · 2023Article
- GeMo: a web-based platform for the visualization and curation of genome ancestry mosaics.Database : the journal of biological databases and curation · 2022Article
- Genetic Ancestry Inference and Its Application for the Genetic Mapping of Human Diseases.International journal of molecular sciences · 2021Review
- A Chromosome-Painting-Based Pipeline to Infer Local Ancestry under Limited Source Availability.Genome biology and evolution · 2021Article
- Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power.Nature genetics · 2021Article
- Systematic Review on Local Ancestor Inference From a Mathematical and Algorithmic Perspective.Frontiers in genetics · 2021Review
- Local ancestry inference provides insight into Tilapia breeding programmes.Scientific reports · 2020Article
- Simulation-Based Evaluation of Three Methods for Local Ancestry Deconvolution of Non-model Crop Species Genomes.G3 (Bethesda, Md.) · 2020Article
- Dating admixture events is unsolved problem in multi-way admixed populations.Briefings in bioinformatics · 2020Article
- Comparing local ancestry inference models in populations of two- and three-way admixture.PeerJ · 2020Article
- The spatial scale of dispersal revealed by admixture tracts.Evolutionary applications · 2019Article
- Fine Scale Genomic Signals of Admixture and Alien Introgression among Asian Rice Landraces.Genome biology and evolution · 2019Article
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6 authors.
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Abstract
Over the past decade, studies of admixed populations have increasingly gained interest in both medical and population genetics. These studies have so far shed light on the patterns of genetic variation throughout modern human evolution and have improved our understanding of the demographics and adaptive processes of human populations. To date, there exist about 20 methods or tools to deconvolve local ancestry. These methods have merits and drawbacks in estimating local ancestry in multiway admixed populations. In this article, we survey existing ancestry deconvolution methods, with special emphasis on multiway admixture, and compare these methods based on simulation results reported by different studies, computational approaches used, including mathematical and statistical models, and biological challenges related to each method. This should orient users on the choice of an appropriate method or tool for given population admixture characteristics and update researchers on current advances, challenges and opportunities behind existing ancestry deconvolution methods.
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