ArticleJornal brasileiro de nefrologia
Epidemiological, clinical, and laboratory factors associated with chronic kidney disease in Mexican HIV-infected patients.
Article in Jornal brasileiro de nefrologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Article
- Structural and functional kidney abnormalities in patients with Human immunodeficiency virus infection: A cross-sectional perspective.World journal of nephrology · 2025Article
- Prevalence of Chronic Kidney Disease and Associated Factors Among Adult HIV/AIDS Patients on HAART in Hiwot Fana Comprehensive Specialized Hospital, Eastern Ethiopia: A Cross-Sectional Study.Health science reports · 2025Article
- Gut-derived bacterial toxins impair memory CD4+ T cell mitochondrial function in HIV-1 infection.The Journal of clinical investigation · 2022Article
- Prevalence and risk factors of chronic kidney disease in an HIV positive Mexican cohort.BMC nephrology · 2021Article
- Factors associated to chronic kidney disease in people living with HIV/AIDS.Revista latino-americana de enfermagem · 2020Article
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5 authors.
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Abstract
aimTo determine the prevalence of chronic kidney disease (CKD) and the epidemiological, clinical, and laboratory factors associated with CKD in Mexican HIV-infected patients.
methodsCross-sectional study. We included 274 patients with HIV/AIDS. CKD was defined by the estimated glomerular filtration rate (eGFR < 60 mL/min/1.73 m2 assessed by CKD-EPI) and albuminuria criteria from KDIGO guidelines. Clinical, epidemiological, and laboratory characteristics were compared between patients with and without CKD. The factors associated with CKD were assessed by logistic regression analysis.
resultsThe mean age was 41±11 years, and 72.3% of the patients were men. The global prevalence of CKD was 11.7% (n = 32); 7.2% (n = 20) were defined by eGFR criterion; 7.6% (n = 21), by the albuminuria criterion; and 3.2% (n = 9), by both CKD criteria. The most frequently observed stages of CKD were KDIGO G3A1 stage with 4.7% (n = 13), KDIGO G1A2 stage with 3.6% (n = 10) and KDIGO G3A2 stage with 1.7% (n = 5). The factors associated with CKD were use of abacavir/lamivudine (OR 3.2; 95% CI 1.1-8.9; p = 0.03), a CD4 lymphocyte count < 400 cells/µL (OR 2.6; 95% 1.03-6.4, p = 0.04), age (OR 1.1; 95% CI 1.04-1.2, p = 0.001) and albuminuria (OR 19.98; 95% CI: 5.5-72.2; p < 0.001).
conclusionsCKD was a frequent complication in HIV-infected patients. These findings confirm the importance of screening and the early detection of CKD, as well as the importance of identifying and treating traditional and non-traditional risk factors associated with CKD.
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