ArticleIEEE transactions on biomedical circuits and systems2018
A High-Resolution Opto-Electrophysiology System With a Miniature Integrated Headstage.
Article in IEEE transactions on biomedical circuits and systems, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Low-power analog and mixed-signal circuit techniques for next-generation miniature implantable neural interface systems.Biomedical engineering letters · 2026Review
- Wireless closed-loop deep brain stimulation using microelectrode array probes.Journal of Zhejiang University. Science. B · 2024Review
- Manufacturing Processes of Implantable Microelectrode Array for In Vivo Neural Electrophysiological Recordings and Stimulation: A State-Of-the-Art Review.Journal of micro- and nano-manufacturing · 2022Article
- In Vivo Penetrating Microelectrodes for Brain Electrophysiology.Sensors (Basel, Switzerland) · 2022Review
- Double-Sided Sapphire Optrodes with Conductive Shielding Layers to Reduce Optogenetic Stimulation Artifacts.Micromachines · 2022Article
- Neural microprobe modelling and microfabrication for improved implantation and mechanical failure mitigation.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2022Article
- Active Dendrites and Local Field Potentials: Biophysical Mechanisms and Computational Explorations.Neuroscience · 2022Review
- Influence of the Surface Material and Illumination upon the Performance of a Microelectrode/Electrolyte Interface in Optogenetics.Micromachines · 2021Article
- Parylene photonics: a flexible, broadband optical waveguide platform with integrated micromirrors for biointerfaces.Microsystems & nanoengineering · 2020Article
- Recent Progress on Non-Conventional Microfabricated Probes for the Chronic Recording of Cortical Neural Activity.Sensors (Basel, Switzerland) · 2019Review
- Receptor variants and the development of centrally acting medications .Dialogues in clinical neuroscience · 2019Article
- Implantable Neural Probes for Brain-Machine Interfaces - Current Developments and Future Prospects.Experimental neurobiology · 2018Review
- The History and Horizons of Microscale Neural Interfaces.Micromachines · 2018Article
- A High-Resolution Opto-Electrophysiology System With a Miniature Integrated Headstage.IEEE transactions on biomedical circuits and systems · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
This work presents a fully integrated neural interface system in a small form factor (1.9 g), consisting of a μLED silicon optoelectrode (12 μLEDs and 32 recording sites in a 4-shank configuration), an Intan 32-channel recording chip, and a custom optical stimulation chip for controlling 12 μLEDs. High-resolution optical stimulation with approximately 68.5 nW radiant flux resolution is achieved by a custom LED driver ASIC, which enables individual control of up to 48 channels with a current precision of 1 μA, a maximum current of 1.024 mA, and an update rate of >10 kHz. Recording is performed by an off-the-shelf 32-channel digitizing front-end ASIC from Intan. Two compact custom interface printed circuit boards were designed to link the headstage with a PC. The prototype system demonstrates precise current generation, sufficient optical radiant flux generation , and fast turn-on of μLEDs . Single animal in vivo experiments validated the headstage's capability to precisely modulate single neuronal activity and independently modulate activities of separate neuronal populations near neighboring optoelectrode shanks.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.