Evidence map›Paper›PMID 30009168›Full record

ArticleBioMed research international2018

CD4

Helena L Silva-Neta, Maria C A Brelaz-de-Castro, Mardonny B O Chagas, Henrique A Mariz, Rodrigo G de Arruda, Viviane F de Vasconcelos, Michelly C Pereira, Audrey Romano, Ivan R Pitta, Claudia D L Marques and 3 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Helena L Silva-NetaLaboratório de Imunomodulação e Novas Abordagens Terapêuticas (LINAT), Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino (NUPIT-SG), Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.
Maria C A Brelaz-de-CastroLaboratório de Parasitologia, Centro Acadêmico de Vitória, Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.ORCID 0000-0003-2205-0618
Mardonny B O ChagasLaboratório de Imunomodulação e Novas Abordagens Terapêuticas (LINAT), Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino (NUPIT-SG), Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.
Henrique A MarizLaboratório de Imunomodulação e Novas Abordagens Terapêuticas (LINAT), Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino (NUPIT-SG), Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.
Rodrigo G de ArrudaFaculdade Nova Roma, 50830-260, Brazil.
Viviane F de VasconcelosHospital das Clínicas, Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.
Michelly C PereiraLaboratório de Imunomodulação e Novas Abordagens Terapêuticas (LINAT), Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino (NUPIT-SG), Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.ORCID 0000-0002-1672-8202
Audrey RomanoCentre for Immunology & Infection, Department of Biology and Hull York Medical School, University of York, YO10 5DD, UK.
Ivan R PittaLaboratório de Imunomodulação e Novas Abordagens Terapêuticas (LINAT), Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino (NUPIT-SG), Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.
Claudia D L MarquesLaboratório de Imunomodulação e Novas Abordagens Terapêuticas (LINAT), Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino (NUPIT-SG), Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.
Angela L B P DuarteHospital das Clínicas, Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.
Moacyr J B M RêgoLaboratório de Imunomodulação e Novas Abordagens Terapêuticas (LINAT), Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino (NUPIT-SG), Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.ORCID 0000-0002-1883-6012
Maira G R PittaLaboratório de Imunomodulação e Novas Abordagens Terapêuticas (LINAT), Núcleo de Pesquisa em Inovação Terapêutica Suely Galdino (NUPIT-SG), Universidade Federal de Pernambuco (UFPE), 50670-901, Brazil.ORCID 0000-0001-5881-0338
Universidade Federal de Pernambuco · BRHospital das Clínicas da Universidade Federal de Pernambuco · BRFaculdade Brasil · BRUniversity of York · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heren, we analyzed Treg cells as potential biomarkers of disease activity in systemic lupus erythematosus (SLE) patients. Peripheral blood mononuclear cells from 30 SLE patients (15 active: SLEDAI > 6/15 SLE remission: SLEDAI< 6) and 15 healthy volunteers were purified. Treg immunophenotyping was performed using CD4, CD25, CD45, CD127, and FOXP3 markers. CD4

Indexed as

BiomarkersT-Lymphocytes, RegulatoryAdultBrazilCD4 AntigensFemaleFlow CytometryForkhead Transcription FactorsHumansInterleukin-2 Receptor alpha SubunitLeukocyte Common AntigensLeukocytes, MononuclearLupus Erythematosus, SystemicMaleMiddle AgedYoung AdultBiomarkersCD4 AntigensForkhead Transcription FactorsFOXP3 protein, humanInterleukin-2 Receptor alpha SubunitLeukocyte Common Antigens

Identifiers

PMID30009168
PMCPMC6020667
OpenAlexW2808509362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.