Evidence map›Paper›PMID 30009158›Full record

ReviewCanadian journal of gastroenterology & hepatology2018

Economic Evaluations of Treatments for Inflammatory Bowel Diseases: A Literature Review.

Lachaine Jean, Miron Audrey, Catherine Beauchemin, On Behalf Of The iGenoMed Consortium

Registry-linked trialAbstract readReview
In one paragraph

Review in Canadian journal of gastroenterology & hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05386290 (A Multicentered Prospective Cohort Study of Chinese IBD Patients Concerning Cost-effectiveness Analysis, Therapeutic Effect Predictor Exploration and Gut Microbiota Analysis), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05386290 unknown statusnot on this mapstarted 2020, after this paper: background citation

A Multicentered Prospective Cohort Study of Chinese IBD Patients Concerning Cost-effectiveness Analysis, Therapeutic Effect Predictor Exploration and Gut Microbiota Analysis

TypeobservationalSponsorPeking Union Medical College HospitalRan2020 to 2023Enrolled200ConditionsUlcerative Colitis, Crohn DiseaseArmsInfliximab, Vedolizumab, Ustekinumab, conventional treatment (glucocoticoid, immunosupressive drugs and/or mesalazine)
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Mucosal healing in inflammatory bowel disease: Expanding horizon.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019
    Review
  9. The Impact of Inflammatory Bowel Disease in Canada 2018: IBD Research Landscape in Canada.Journal of the Canadian Association of Gastroenterology · 2019
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lachaine JeanFaculty of Pharmacy, University of Montreal, Montreal, QC, Canada.ORCID 0000-0002-0791-2518
Miron AudreyFaculty of Pharmacy, University of Montreal, Montreal, QC, Canada.
Catherine BeaucheminFaculty of Pharmacy, University of Montreal, Montreal, QC, Canada.
On Behalf Of The iGenoMed ConsortiumMontreal Heart Institute, 5000 Bélanger, Room S-6300, Montreal, QC, Canada H1T 1C8.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The objective of this literature review was to evaluate the existing evidence regarding the cost-effectiveness of treatment options in IBD. Methods: A systematic review of the literature was conducted to identify economic evaluations of IBD therapy. The literature search was performed using electronic databases MEDLINE and EMBASE. Searches were limited to full economic evaluations published in English or French between 2004 and 2016. Results: A total of 5,403 potentially relevant studies were identified. After screening titles and abstracts, 48 studies were included, according to the eligibility criteria. A total of 56% and 42% of the studies were assessing treatments of UC or CD, respectively. Treatment options under evaluation included biological agents, mesalamine, immunosuppressants, and surgery. The majority of studies evaluated the cost-effectiveness of biological treatments. Biological therapies were dominant in 23% of the analyses and were cost-effective according to a $CAD50,000/QALY and $CAD100,000/QALY threshold in 41% and 62% of the analyses, respectively. Conclusion: This literature review provided a comprehensive overview of the economic evaluations for the different treatment options for IBD over the past 12 years and represents a helpful reference for future economic evaluations.

Indexed as

Health Care CostsAnti-Inflammatory Agents, Non-SteroidalBiological ProductsColitis, UlcerativeCost-Benefit AnalysisCrohn DiseaseHumansImmunosuppressive AgentsMesalamineProctocolectomy, RestorativeQuality-Adjusted Life YearsAnti-Inflammatory Agents, Non-SteroidalBiological ProductsImmunosuppressive AgentsMesalamine

Identifiers

PMID30009158
PMCPMC6020513

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.