Evidence map›Paper›PMID 30009009›Full record

ArticleChemical science2018

An ultrasensitive polydopamine bi-functionalized SERS immunoassay for exosome-based diagnosis and classification of pancreatic cancer.

Teng-Da Li, Ren Zhang, Hui Chen, Zhi-Peng Huang, Xin Ye, Hui Wang, An-Mei Deng, Ji-Lie Kong

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 221 citations in OpenAlex.

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  4. SERSµDrop: A Platform to Study Cell-Cell Communication via SERS Imaging.Small (Weinheim an der Bergstrasse, Germany) · 2026
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Teng-Da LiCenter of Clinical Experiments , Changhai Hospital , Second Military Medical University , Shanghai , China 200433.
Ren ZhangDepartment of Chemistry and Institutes of Biomedical Sciences , Fudan University , Shanghai , China 200433 . Email: chenhui@fudan.edu.cn ; Email: jlkong@fudan.edu.cn.
Hui ChenDepartment of Chemistry and Institutes of Biomedical Sciences , Fudan University , Shanghai , China 200433 . Email: chenhui@fudan.edu.cn ; Email: jlkong@fudan.edu.cn.ORCID 0000-0002-2281-5935
Zhi-Peng HuangDepartment of Chemistry and Institutes of Biomedical Sciences , Fudan University , Shanghai , China 200433 . Email: chenhui@fudan.edu.cn ; Email: jlkong@fudan.edu.cn.
Xin YeDepartment of Chemistry and Institutes of Biomedical Sciences , Fudan University , Shanghai , China 200433 . Email: chenhui@fudan.edu.cn ; Email: jlkong@fudan.edu.cn.
Hui WangCenter of Clinical Experiments , Changhai Hospital , Second Military Medical University , Shanghai , China 200433.
An-Mei DengCenter of Clinical Experiments , Changhai Hospital , Second Military Medical University , Shanghai , China 200433.
Ji-Lie KongDepartment of Chemistry and Institutes of Biomedical Sciences , Fudan University , Shanghai , China 200433 . Email: chenhui@fudan.edu.cn ; Email: jlkong@fudan.edu.cn.
Fudan University · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early diagnosis and metastasis monitoring for pancreatic cancer are extremely difficult due to a lack of sensitive liquid biopsy methods and reliable biomarkers. Herein, we developed easy-to-prepare and effective polydopamine-modified immunocapture substrates and an ultrathin polydopamine-encapsulated antibody-reporter-Ag(shell)-Au(core) multilayer (PEARL) Surface-Enhanced Raman Scattering (SERS) nano-tag with a quantitative signal of the Raman reporter at 1072 cm

Identifiers

PMID30009009
PMCPMC6009498
OpenAlexW2803929346

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.