Evidence map›Paper›PMID 30008999›Full record

ArticleChemical science2016

A carboxylesterase-selective ratiometric fluorescent two-photon probe and its application to hepatocytes and liver tissues.

Sang Jun Park, Hyo Won Lee, Hye-Ri Kim, Chulhun Kang, Hwan Myung Kim

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sang Jun ParkDepartment of Chemistry and Department of Energy Systems Research , Ajou University , Suwon 443-749 , Korea . Email: kimhm@ajou.ac.kr.
Hyo Won LeeDepartment of Chemistry and Department of Energy Systems Research , Ajou University , Suwon 443-749 , Korea . Email: kimhm@ajou.ac.kr.
Hye-Ri KimSchool of East-West Medical Science , Kyung Hee University , Yongin 446-701 , Korea . Email: kangch@khu.ac.kr.
Chulhun KangSchool of East-West Medical Science , Kyung Hee University , Yongin 446-701 , Korea . Email: kangch@khu.ac.kr.
Hwan Myung KimDepartment of Chemistry and Department of Energy Systems Research , Ajou University , Suwon 443-749 , Korea . Email: kimhm@ajou.ac.kr.
Yong In University · KRSuwon Research Institute · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carboxylesterases (CEs) are widely distributed enzymes in the human body that catalyze hydrolysis of various endogenous and exogenous substrates. They are directly linked to hepatic drug metabolisms and steatosis, and their regulations are important issues in pharmacological and clinical applications. In this work, we have developed an emission ratiometric two-photon probe (

Identifiers

PMID30008999
PMCPMC6008934
OpenAlexW2275471812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.