ArticleChemical science2016
Efficient metal-free photochemical borylation of aryl halides under batch and continuous-flow conditions.
Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Total Synthesis of (+)-CC-1065.Journal of the American Chemical Society · 2026Article
- Metal-free radical borylations: mechanisms, catalytic strategies, and synthetic applications.Chemical science · 2026Review
- Iodoarene Activation: Take a Leap Forward toward Green and Sustainable Transformations.Chemical reviews · 2025Review
- Article
- Modular Synthesis of Dehydroprolines by an Energy-Transfer Enabled Cloke-Wilson Rearrangement.Angewandte Chemie (International ed. in English) · 2025Article
- Solvent Anions Enable Photoinduced Borylation and Phosphonation of Aryl Halides via EDA Complexes.Organic letters · 2022Article
- Technological Innovations in Photochemistry for Organic Synthesis: Flow Chemistry, High-Throughput Experimentation, Scale-up, and Photoelectrochemistry.Chemical reviews · 2022Review
- Electrochemical borylation of carboxylic acids.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Aerobic Visible-Light-Driven Borylation of Heteroarenes in a Gel Nanoreactor.Organic letters · 2021Article
- Flow Photochemistry as a Tool in Organic Synthesis.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Review
- Coligand role in the NHC nickel catalyzed C-F bond activation: investigations on the insertion of bis(NHC) nickel into the C-F bond of hexafluorobenzene.Chemical science · 2020Article
- Luminescent tungsten(vi) complexes as photocatalysts for light-driven C-C and C-B bond formation reactions.Chemical science · 2020Article
- Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [Nature protocols · 2020Article
- Radical C-N Borylation of Aromatic Amines Enabled by a Pyrylium Reagent.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Article
- Visible Light-Induced Borylation of C-O, C-N, and C-X Bonds.Journal of the American Chemical Society · 2020Article
- New avenues for C-B bond formationChemical science · 2019Review
- Organoboron chemistry comes to light: recent advances in photoinduced synthetic approaches to organoboron compounds.Tetrahedron · 2019Article
- Direct Transformation from Arylamines to Aryl Naphthalene-1,8-diamino Boronamides: A Metal-Free Sandmeyer-Type Process.Molecules (Basel, Switzerland) · 2019Article
- Transition-metal free C-C bond cleavage/borylation of cycloketone oxime esters.Chemical science · 2019Article
- Metal-Free Radical Borylation of Alkyl and Aryl Iodides.Angewandte Chemie (International ed. in English) · 2018Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A rapid, chemoselective and metal-free C-B bond-forming reaction of aryl iodides and bromides in aqueous solution at low temperatures was discovered. This reaction is amenable to batch and continuous-flow conditions and shows exceptional functional group tolerance and broad substrate scope regarding both the aryl halide and the borylating reagent. Initial mechanistic experiments indicated a photolytically generated aryl radical as the key intermediate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.