ArticleCurrent protocols in immunology2018
Gnotobiotic and Conventional Mouse Systems to Support Microbiota Based Studies.
Article in Current protocols in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Insights into Microbiota-Vaccine Crosstalk in Humans: Mechanisms, Modulators, and Translational Horizons.Vaccines · 2026Review
- The elephant (bird) in the room: unknown mechanisms and unresolved impacts of low DNA yields in avian microbiome research.Animal microbiome · 2026Article
- Optimized cesarean techniques, IVF use, and foster strain selection enhance germ-free mouse production efficiency.Scientific reports · 2025Article
- Article
- Causal inference on microbiome-metabolome relations in observational host-microbiome data via in silico in vivo association pattern analyses.Cell reports methods · 2023Article
- Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.The Journal of experimental medicine · 2023Article
- SEQ2MGS: an effective tool for generating realistic artificial metagenomes from the existing sequencing data.NAR genomics and bioinformatics · 2022Article
- Protocol for using negative pressure isolator systems to study BSL-2 organisms in gnotobiotic murine models.STAR protocols · 2022Article
- In vivo commensal control of Clostridioides difficile virulence.Cell host & microbe · 2021Article
- Proanthocyanidin-enriched cranberry extract induces resilient bacterial community dynamics in a gnotobiotic mouse model.Microbial cell (Graz, Austria) · 2021Article
- Methods for Establishment and Maintenance of Germ-Free Rat Models.Frontiers in microbiology · 2020Article
- The emerging roles of the gut microbiome in allogeneic hematopoietic stem cell transplantation.Gut microbesReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Animal models are essential to dissect host-microbiota interactions that impact health and the development of disease. In addition to providing pre-clinical models for the development of novel therapeutics and diagnostic biomarkers, mouse systems actively support microbiome studies by defining microbial contributions to normal development and homeostasis, and as well as their role in promoting diseases such as inflammatory auto-immune diseases, diabetes, metabolic syndromes, and susceptibilities to infectious agents. Mice provide a genetically tenable host that can be reared under gnotobiotic (germfree) conditions, allowing colonization studies with human or mouse-origin defined or complex microbial communities to define specific
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.