ReviewDisease markers2018
Urinary Biochemistry in the Diagnosis of Acute Kidney Injury.
Review in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed.
- Comprehensive biomarker assessment for predicting severe acute kidney injury and need of kidney replacement therapy in liver transplantation patients.Renal failure · 2024Trial
- Article
- COVID-19 associated acute kidney injury.Infectious diseases & immunity · 2025Review
- Renal profile and the associated outcome of patients with acute kidney injury undergoing dialysis in Renal Unit at a Tertiary Healthcare Facility in Western Kenya.African health sciences · 2025Article
- Metabolic Chaos in Kidney Disease: Unraveling Energy Dysregulation.Journal of clinical medicine · 2024Review
- Fractional excretion of urea nitrogen can identify true worsening renal function in patients with heart failure.ESC heart failure · 2024Article
- Urine output is an early and strong predictor of acute kidney injury and associated mortality: a systematic literature review of 50 clinical studies.Annals of intensive care · 2024Review
- The Role of Biomarkers in Diagnosis of Sepsis and Acute Kidney Injury.Biomedicines · 2024Review
- Utility of fractional excretion of urea nitrogen in heart failure patients with chronic kidney disease.ESC heart failure · 2023Article
- Identification of Pre-Renal and Intrinsic Acute Kidney Injury by Anamnestic and Biochemical Criteria: Distinct Association with Urinary Injury Biomarkers.International journal of molecular sciences · 2023Article
- New Classification for the Combined Assessment of the Fractional Excretion of Urea Nitrogen and Estimated Plasma Volume Status in Acute Heart Failure.Journal of the American Heart Association · 2023Article
- The Risk and Clinical Implications of Antibiotic-Associated Acute Kidney Injury: A Review of the Clinical Data for Agents with Signals from the Food and Drug Administration's Adverse Event Reporting System (FAERS) Database.Antibiotics (Basel, Switzerland) · 2022Review
- Diagnosis of Cardiac Surgery-Associated Acute Kidney Injury: State of the Art and Perspectives.Journal of clinical medicine · 2022Review
- Role of proenkephalin in the diagnosis of severe and subclinical acute kidney injury during the perioperative period of liver transplantation.Practical laboratory medicine · 2022Article
- Urinary tubular biomarkers as predictors of death in critically ill patients with COVID-19.Biomarkers in medicine · 2022Article
- Alerting to acute kidney injury - Challenges, benefits, and strategies.Practical laboratory medicine · 2022Article
- Exploring urine:serum fractional excretion ratios as potential biomarkers for lupus nephritis.Frontiers in immunology · 2022Article
- Reduced inflammation following human endometrial stromal/stem cell injection into male Wistar rats with cisplatin-induced acute kidney injury.BioImpacts : BI · 2022Article
- Prognostic Value of Fractional Excretion of Urea Nitrogen at Discharge in Acute Decompensated Heart Failure.Journal of the American Heart Association · 2021Article
- Association between Urinary Potassium Excretion and Acute Kidney Injury in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute kidney injury (AKI) is a common complication, impacting short- and long-term patient outcomes. Although the application of the classification systems for AKI has improved diagnosis, early clinical recognition of AKI is still challenging, as increments in serum creatinine may be late and low urine output is not always present. The role of urinary biochemistry has remained unclear, especially in critically ill patients. Differentiating between a transient and persistent acute kidney injury is of great need in clinical practice, and despite studies questioning their application in clinical practice, biochemistry indices continue to be used while we wait for a novel early injury biomarker. An ideal marker would provide more detailed information about the type, intensity, and location of the injury. In this review, we will discuss factors affecting the fractional excretion of sodium (FeNa) and fractional excretion of urea (FeU). We believe that the frequent assessment of urinary biochemistry and microscopy can be useful in evaluating the likelihood of AKI reversibility. The availability of early injury biomarkers could help guide clinical interventions.
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