Evidence map›Paper›PMID 30008838›Full record

ArticleOncology letters2018

EPCR promotes MGC803 human gastric cancer cell tumor angiogenesis

Qingling Wang, Yangyang Tang, Tianyuan Wang, Hong-Li Yang, Xinyue Wang, Hongru Ma, Peng Zhang

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Qingling WangDepartment of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China.
Yangyang TangDepartment of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China.
Tianyuan WangDepartment of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China.
Hong-Li YangDepartment of Pathology, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China.
Xinyue WangSchool of Anesthesiology, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China.
Hongru MaSchool of Clinical Medicine, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P.R. China.
Peng ZhangJiangsu Key Laboratory of Immunity and Metabolism, Xuzhou, Jiangsu 221004, P.R. China.
Xuzhou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endothelial cell protein C receptor (EPCR) serves a key role in activated protein C (APC)-mediated cytoprotective effects in endothelial cells, and is involved in the development of certain types of human cancer. To the best of our knowledge, the present study is the first to demonstrate that EPCR may exert effects on gastric cancer angiogenesis

Indexed as

endothelial protein C receptorextracellular signal regulated kinase 1/2gastric cancerprotease-activated receptor 1protein kinase Btumor angiogenesis

Identifiers

PMID30008838
PMCPMC6036513
OpenAlexW2805086984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.