Evidence map›Paper›PMID 30008832›Full record

ArticleOncology letters2018

Discrimination of malignant and benign breast masses using automatic segmentation and features extracted from dynamic contrast-enhanced and diffusion-weighted MRI.

Xinhua Jiang, Fei Xie, Lizhi Liu, Yanxia Peng, Hongmin Cai, Li Li

Abstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Dynamic contrast-enhanced MRI radiomics nomogram for predicting axillary lymph node metastasis in breast cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2022
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Machine learning in breast MRI.Journal of magnetic resonance imaging : JMRI · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. The Application of Radiomics in Breast MRI: A Review.Technology in cancer research & treatment
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinhua JiangDepartment of Medical Imaging, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China.
Fei XieDepartment of Medical Imaging, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China.
Lizhi LiuDepartment of Medical Imaging, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China.
Yanxia PengDepartment of Radiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, P.R. China.
Hongmin CaiDepartment of Computer Science, School of Computer Science and Engineering, South China University of Technology, Guangzhou, Guangdong 510006, P.R. China.
Li LiDepartment of Medical Imaging, Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic resonance imaging exhibits high sensitivity but low specificity for breast cancer. The present study aimed to investigate whether combining morphology, texture features and kinetic features with diffusion-weighted imaging using quantitative analysis improves the accuracy of discriminating malignant from benign breast masses. In total, 104 and 171 malignant lesions in 205 women were included. Additionally, 13 texture and 11 morphology features were computed from each lesion using a semi-automated segmentation method. To increase prediction accuracy, a newly designed classification model, difference-weighted local hyperplane, was used for statistical analysis of the combined effects of the features for predicting lesion type. The mean apparent diffusion coefficient (ADC) value for each lesion was calculated. Diagnostic performances of morphology and texture features, kinetic features and ADC alone and the combination of them were evaluated using receiver operating characteristics analysis. Malignant lesions had lower mean ADCs than benign lesions. By using 10-fold cross validation scheme, combined morphological and kinetic features achieved a diagnostic average accuracy of 0.87. Adding an ADC threshold of 1.37×10

Indexed as

breast masscomputer-aided diagnosisdifference-weighted local hyperplanediffusion-weighted imagingquantitative morphology and texture features

Identifiers

PMID30008832
PMCPMC6036451

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.