Evidence map›Paper›PMID 30008742›Full record

ArticleNeural plasticity2018

Impact of Global Mean Normalization on Regional Glucose Metabolism in the Human Brain.

Kristian N Mortensen, Albert Gjedde, Garth J Thompson, Peter Herman, Maxime J Parent, Douglas L Rothman, Ron Kupers, Maurice Ptito, Johan Stender, Steven Laureys and 3 more

Open access · goldAbstract read
In one paragraph

Article in Neural plasticity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. In vivo neuropil density from anatomical MRI and machine learning.Cerebral cortex (New York, N.Y. : 1991) · 2024
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  7. High-resolution relaxometry-based calibrated fMRI in murine brain: Metabolic differences between awake and anesthetized states.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  8. EANM procedure guidelines for brain PET imaging using [European journal of nuclear medicine and molecular imaging · 2022
    Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 5 countries.

Kristian N MortensenDepartment of Radiology & Biomedical Imaging and Magnetic Resonance Research Center, Yale University, New Haven, CT, USA.
Albert GjeddeDepartment of Neuroscience, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-3756-7401
Garth J ThompsonDepartment of Radiology & Biomedical Imaging and Magnetic Resonance Research Center, Yale University, New Haven, CT, USA.
Peter HermanDepartment of Radiology & Biomedical Imaging and Magnetic Resonance Research Center, Yale University, New Haven, CT, USA.ORCID 0000-0003-2218-9652
Maxime J ParentDepartment of Radiology & Biomedical Imaging and Magnetic Resonance Research Center, Yale University, New Haven, CT, USA.ORCID 0000-0003-3996-4029
Douglas L RothmanDepartment of Radiology & Biomedical Imaging and Magnetic Resonance Research Center, Yale University, New Haven, CT, USA.
Ron KupersDepartment of Neuroscience, University of Copenhagen, Copenhagen, Denmark.
Maurice PtitoDepartment of Neuroscience, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-5173-5862
Johan StenderDepartment of Neuroscience, University of Copenhagen, Copenhagen, Denmark.
Steven LaureysGIGA-Consciousness, Coma Science Group, Université de Liège, Liège, Belgium.
Valentin RiedlDepartments of Neuroradiology, Nuclear Medicine and Neuroimaging Center, Technische Universität München, München, Germany.
Michael T AlkireDepartment of Anesthesiology, University of California, Irvine, CA, USA.
Fahmeed HyderDepartment of Radiology & Biomedical Imaging and Magnetic Resonance Research Center, Yale University, New Haven, CT, USA.ORCID 0000-0001-7822-4002
University of Copenhagen · DKYale University · USTechnical University of Munich · DEUniversity of California, Irvine · USUniversity of Liège · BE

Funding

NeurophysiologicP30NS052519 · NINDS · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2007 to 2017
$6.7M
Energetics of Neuronal Populations by fMRIR01MH067528 · NIMH · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2002 to 2021
$5.9M
MRS validation of computational metabolic modeling of human brain function to determine energetic disruptions underlying fMRI-derived functional connectivity in degenerative or psychiatric disordersR01NS100106 · NINDS · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED, ROTHMAN, DOUGLAS LYLE · 2017 to 2021
$959k
NIMH NIH HHS R01 MH067528NINDS NIH HHS P30 NS052519NINDS NIH HHS R01 NS100106
6 · The paper itself

Abstract

Because the human brain consumes a disproportionate fraction of the resting body's energy, positron emission tomography (PET) measurements of absolute glucose metabolism (CMR

Indexed as

AdultBlindnessBrainData Interpretation, StatisticalFemaleGlucoseHumansImage Processing, Computer-AssistedMaleMiddle AgedPositron-Emission TomographySignal Processing, Computer-AssistedYoung AdultGlucose

Identifiers

PMID30008742
PMCPMC6020504
OpenAlexW2807777575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.