Evidence map›Paper›PMID 30008674›Full record

ArticleFrontiers in physiology2018

Melatonin Relations With Respiratory Quotient Weaken on Acute Exposure to High Altitude.

Marcelo Tapia, Cristian Wulff-Zottele, Nicole De Gregorio, Morin Lang, Héctor Varela, María Josefa Serón-Ferré, Ennio A Vivaldi, Oscar F Araneda, Juan Silva-Urra, Hanns-Christian Gunga and 1 more

Abstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Metabolic flexibility during sleep.Scientific reports · 2021
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marcelo TapiaOwl Capacitaciones y Asesorías SpA, Antofagasta, Chile.
Cristian Wulff-ZotteleFacultad de Ciencias de la Salud, Universidad de Antofagasta, Antofagasta, Chile.
Nicole De GregorioFacultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.
Morin LangFacultad de Ciencias de la Salud, Universidad de Antofagasta, Antofagasta, Chile.
Héctor VarelaFacultad de Ciencias Básicas, Universidad de Antofagasta, Antofagasta, Chile.
María Josefa Serón-FerréFacultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.
Ennio A VivaldiFacultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.
Oscar F AranedaFacultad de Medicina, Universidad de los Andes, Santiago, Chile.
Juan Silva-UrraFacultad de Ciencias de la Salud, Universidad de Antofagasta, Antofagasta, Chile.
Hanns-Christian GungaCenter for Space Medicine and Extreme Environments, Institute of Physiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Claus BehnFacultad de Medicina, Instituto de Ciencias Biomédicas, Universidad de Chile, Santiago, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High altitude (HA) exposure may affect human health and performance by involving the body timing system. Daily variations of melatonin may disrupt by HA exposure, thereby possibly affecting its relations with a metabolic parameter like the respiratory quotient (RQ). Sea level (SL) volunteers (7 women and 7 men, 21.0 ± 2.04 y) were examined for daily changes in salivary melatonin concentration (SMC). Sampling was successively done at SL (Antofagasta, Chile) and, on acute HA exposure, at nearby Caspana (3,270 m asl). Saliva was collected in special vials (Salimetrics Oral Swab, United Kingdom) at sunny noon (SMC

Indexed as

body timekeepingcircadian rhythmhigh altitudemelatoninrespiratory quotient

Identifiers

PMID30008674
PMCPMC6034204

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.