Evidence map›Paper›PMID 30008628›Full record

ArticleMetabolomics : Official journal of the Metabolomic Society2018

Metabolomics reveals immunomodulation as a possible mechanism for the antibiotic effect of

Pei Han, Yong Huang, Yumin Xie, Wu Yang, Wenying Xiang, Peter J Hylands, Cristina Legido-Quigley

Open access · hybridAbstract read
In one paragraph

Article in Metabolomics : Official journal of the Metabolomic Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 16 citations in OpenAlex.

  1. Itaconate and its derivatives in human health and diseases.Signal transduction and targeted therapy · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Pei HanInstitute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, London, SE1 9NH, UK.
Yong HuangProvincial Key Laboratory of Pharmaceutics in Guizhou Province, School of Pharmacy, Guizhou Medical University, Guiyang, Guizhou, China.
Yumin XieProvincial Key Laboratory of Pharmaceutics in Guizhou Province, School of Pharmacy, Guizhou Medical University, Guiyang, Guizhou, China.
Wu YangProvincial Key Laboratory of Pharmaceutics in Guizhou Province, School of Pharmacy, Guizhou Medical University, Guiyang, Guizhou, China.
Wenying XiangProvincial Key Laboratory of Pharmaceutics in Guizhou Province, School of Pharmacy, Guizhou Medical University, Guiyang, Guizhou, China.
Peter J HylandsInstitute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, London, SE1 9NH, UK. peter.2.hylands@kcl.ac.uk.
Cristina Legido-QuigleyInstitute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College London, London, SE1 9NH, UK. cristina.legido.quigley@regionh.dk.
Guiyang Medical University · CNKing's College London · GBSteno Diabetes Center · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn spite of advances in antibiotics, urinary tract infection (UTI) is still among the most common reasons for antibiotic medication worldwide.

objectiveThe objective of this study was to explore the working mechanism of

methods

resultsThe results showed that after the treatments, urine levels of itaconic acid in

conclusionOur findings suggest that this herbal medicine can cure urinary tract infection through modulation of immune system.

Indexed as

ImmunomodulationMetabolomicsP. capitataUrinary tract infection

Identifiers

PMID30008628
PMCPMC6019430
OpenAlexW2811306341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.