Evidence map›Paper›PMID 30008620›Full record

ReviewThrombosis journal2018

Differences and similarities between disseminated intravascular coagulation and thrombotic microangiopathy.

Hideo Wada, Takeshi Matsumoto, Kei Suzuki, Hiroshi Imai, Naoyuki Katayama, Toshiaki Iba, Masanori Matsumoto

Abstract readReview
In one paragraph

Review in Thrombosis journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hideo Wada1Department of Molecular and Laboratory Medicine, Mie University Graduate School of Medicine, Tsu, Mie 514-8507 Japan.ORCID 0000-0001-9021-8633
Takeshi Matsumoto2Division of Blood Transfusion Medicine and Cell Therapy, Mie University Graduate School of Medicine, Tsu, Japan.
Kei Suzuki3Emergency Critical Care Center, Mie University Graduate School of Medicine, Tsu, Japan.
Hiroshi Imai3Emergency Critical Care Center, Mie University Graduate School of Medicine, Tsu, Japan.
Naoyuki Katayama4Department of Hematology and Oncology, Mie University Graduate School of Medicine, Tsu, Japan.
Toshiaki Iba5Department of Emergency and Disaster Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Masanori Matsumoto6Department of Blood Transfusion Medicine, Nara Medical University, Nara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBoth disseminated intravascular coagulation (DIC) and thrombotic microangiopathy (TMA) cause microvascular thrombosis associated with thrombocytopenia, bleeding tendency and organ failure. REPORTS AND DISCUSSION: The frequency of DIC is higher than that of thrombotic thrombocytopenic purpura (TTP). Many patients with TMA are diagnosed with DIC, but only about 15% of DIC patients are diagnosed with TMA. Hyperfibrinolysis is observed in most patients with DIC, and microangiopathic hemolytic anemia is observed in most patients with TMA. Markedly decreased ADAMTS13 activity, the presence of Shiga-toxin-producing

conclusionAlthough DIC and TMA are similar appearances, all coagulation, fibrinolysis and platelet systems are activated in DIC, and only platelets are markedly activated in TMA.

Indexed as

DICHyperfibrinolysisMicroangiopathic hemolytic anemiaMicrovascular thrombosisOrgan failureTMA

Identifiers

PMID30008620
PMCPMC6040080

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.