ReviewThe obstetrician & gynaecologist : the journal for continuing professional development from the Royal College of Obstetricians & Gynaecologists2018
Spontaneous preterm birth prevention in multiple pregnancy.
Review in The obstetrician & gynaecologist : the journal for continuing professional development from the Royal College of Obstetricians & Gynaecologists, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Mode of delivery and neonatal outcomes in preterm twins less than 32 weeks of gestation or birthweight under 1500 g: a systematic review and meta-analyses.Archives of gynecology and obstetrics · 2024Pooled it
- Vaginal progesterone for preventing preterm birth and adverse perinatal outcomes in twin gestations: a systematic review and meta-analysis.American journal of obstetrics and gynecology · 2023Pooled it
- Is intimate partner violence and obstetrics characteristics of pregnant women associated with preterm birth in Ethiopia? Umbrella review on preterm birth.Reproductive health · 2023Pooled it
- Consequences of cervical pessary for subsequent pregnancy: follow-up of randomized clinical trial (ProTWIN).Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2022Trial
- Child outcomes after placement of a cervical pessary in women with a multiple pregnancy: A 4-year follow-up of the ProTWIN trial.Acta obstetricia et gynecologica Scandinavica · 2019Trial
- Predictive value of a short cervix in the early third trimester for preterm birth in twin pregnancies.BMC pregnancy and childbirth · 2026Article
- Association of adverse pregnancy outcomes and intimate partner violence survivorship: a cross-sectional survey.Frontiers in global women's health · 2026Article
- Assessment of novel sonographic and biochemical tools for spontaneous preterm birth prediction in asymptomatic twin pregnancies.Acta obstetricia et gynecologica Scandinavica · 2025Article
- Unveiling the pathways: identifying the multifaceted determinants of low birth weight among neonates in low-income countries: a case-control study.BMJ public health · 2025Article
- Hepcidin, ferroportin, and hemoglobin as predictors of iron deficiency anemia risk and perinatal outcomes in twin pregnancy.Frontiers in medicine · 2025Article
- Article
- Developing a logistic regression model to predict spontaneous preterm birth from maternal socio-demographic and obstetric history at initial pregnancy registration.BMC pregnancy and childbirth · 2024Article
- The Strong Correlation Between Multiple Births and Preterm Birth Rates in Greece From 1991 to 2022.Cureus · 2024Article
- Cervical elastography: finding a novel predictor for improving the prediction of preterm birth in uncomplicated twin pregnancies.Archives of gynecology and obstetrics · 2024Article
- Evaluating the relationship between conditional cash transfer programme on preterm births: a retrospective longitudinal study using the 100 million Brazilian cohort.BMC public health · 2024Article
- Effects of polydimethylsiloxane membrane surface treatments on human uterine smooth muscle cell strain response.Bioactive materials · 2024Article
- Randomised placebo-controlled trial of antenatal corticosteroids for planned birth in twins (STOPPIT-3): study protocol.BMJ open · 2024Article
- Development and validation of a risk prediction model for spontaneous preterm birth.American journal of translational research · 2024Article
- Reduction in spontaneous and iatrogenic preterm births in twin pregnancies during COVID-19 lockdown in Melbourne, Australia: a multicenter cohort study.BMC pregnancy and childbirth · 2023Article
- Risk Factors Associated with Preterm Birth at a Tertiary Teaching Hospital in Dar es Salaam, Tanzania: An Unmatched Case-Control Study.Rwanda journal of medicine and health sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
key contentTwin pregnancies are associated with a three-fold greater perinatal mortality than singleton pregnancies. Prematurity is a main contributor, with 50% of twin pregnancies delivering before 37 weeks and 10% delivering before 32 weeks of gestation.The aetiology of preterm delivery in twin pregnancies is likely multifactorial and different from that of singletons.Cervical cerclage reduces preterm birth rates in singletons but has mixed results in twins with some studies showing harm.The use of progesterone to prevent preterm birth in singletons has conflicting results and has not been proven to prevent preterm birth in twins. Studies continue to determine whether the cervical pessary is effective in preventing preterm birth in multiple pregnancies.There is a paucity of data available on the prevention of preterm birth in triplets/higher order multiples but similar principles to twin pregnancy apply. LEARNING
objectivesTo review the burden of preterm birth in multiple pregnancy.To understand the methods available for preventing preterm birth in multiple pregnancies and the evidence surrounding the use of each one.To be aware of the use of the Arabin pessary.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.