Evidence map›Paper›PMID 30008585›Full record

ArticleInternational journal of medical sciences2018

Correlation of E-cadherin gene polymorphisms and epidermal growth factor receptor mutation in lung adenocarcinoma.

Chun-Yao Huang, Ming-Ju Hsieh, Tu-Chen Liu, Whei-Ling Chiang, Ming-Che Liu, Shun-Fa Yang, Thomas Chang-Yao Tsao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Chun-Yao HuangInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Ming-Ju HsiehInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Tu-Chen LiuInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Whei-Ling ChiangSchool of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.
Ming-Che LiuDepartment of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, United States.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Thomas Chang-Yao TsaoSchool of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Chung Shan Medical University · TWChina Medical University · TWChung Shan Medical University Hospital · TWUniversity of Massachusetts Amherst · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial-mesenchymal transition (EMT) was recently discovered related to the efficacy of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) in NSCLC patients and cell lines. In this study, we aimed to explore the association among the E-cadherin gene (

Indexed as

AdenocarcinomaAdenocarcinoma of LungAdultAgedAntigens, CDCadherinsErbB ReceptorsFemaleHumansLung NeoplasmsMaleMiddle AgedMutationProtein Kinase InhibitorsTaiwanAntigens, CDCadherinsCDH1 protein, humanErbB ReceptorsProtein Kinase InhibitorsAdenocarcinomaCDH1 geneE-cadherinEpidermal growth factor receptorGenetic variantsPolymorphism

Identifiers

PMID30008585
PMCPMC6036082
OpenAlexW2806768688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.