Evidence map›Paper›PMID 30008055›Full record

ArticleFolia microbiologica2019

Analysis of the effects of mesoporous silica particles SBA-15 and SBA-16 in Streptococcus pneumoniae transformation process.

Maria-Cecília Krähenbühl Amstalden, José Diogo Oliveira, Mathias Strauss, Italo Odone Mazali, Daisy Machado, Thais Holtz Theisen, Marcelo Lancellotti

Abstract read
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In one paragraph

Article in Folia microbiologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maria-Cecília Krähenbühl AmstaldenDepartment of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil.
José Diogo OliveiraDepartment of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil.
Mathias StraussBrazilian Nanotechnology National Laboratory, National Center for Research in Energy and Materials, Campinas, SP, Brazil.
Italo Odone MazaliFunctional Materials Laboratory, Institute of Chemistry, University of Campinas, Campinas, SP, Brazil.
Daisy MachadoDepartment of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil.
Thais Holtz TheisenDepartment of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil.
Marcelo LancellottiDepartment of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil. marcelo.lancellotti@fcf.unicamp.br.ORCID http://orcid.org/0000-0003-2573-9138
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

FAPESP 2011/14079-2FAPESP 2012/15046-3
6 · The paper itself

Abstract

Streptococcus pneumoniae are natural competent bacteria which requires the presence of a pheromone-like molecule to do the transformation process. This study verified the influence of mesoporous silica (SBA-15 and SBA-16) on the transformation process in S. pneumoniae using a donor DNA obtained from a mutant strain of this microorganism (Sp360∆luxS). The results showed that mesoporous silica SBA-15 and SBA-16 particles doubled the transformation ratio frequency compared with negative control (without nanoparticles) in using SBA-15 (ratio 1.81 ± 0.04) and SBA-16 (ratio 2.18 ± 0.22). We demonstrated the how mesoporous silica nanoparticles were able to increase the pneumococcus transformations, which could possibly lead to the acquisition of virulence factor genes and resistance of antibiotics.

Indexed as

Air PollutantsEscherichia coliParticle SizePlasmidsSilicon DioxideStreptococcus pneumoniaeSurface PropertiesTransformation, BacterialAir PollutantsSBA-15SBA-16Silicon Dioxide

Identifiers

PMID30008055
OpenAlexW2882972337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.