ArticleBMJ open2018
Health-related quality of life, participation, and physical and cognitive function of patients with intensive care unit-acquired muscle weakness 1 year after rehabilitation in Germany: the GymNAST cohort study.
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04527627 (Development and Evaluation of a Nursing Intervention in the Patient Being Discharged From the Intensive Care Unit), which is not on this map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Development and Evaluation of a Nursing Intervention in the Patient Being Discharged From the Intensive Care Unit: a Protocol for Mixed Methods Research
Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Trial
- Prognostic value of day 10 mobilization status for ambulation at hospital discharge in critically ill patients: a historical cohort study in Japan.Acute and critical care · 2026Article
- Long-term recovery of sensorimotor functions and prediction of participation in survivors of critical illness: a prospective cohort study.Journal of intensive care · 2025Article
- Definitions, epidemiology, and outcomes of persistent/chronic critical illness: a scoping review for translation to clinical practice.Critical care (London, England) · 2024Article
- Comprehensive assessment and progression of health status during neurorehabilitation in survivors of critical illness: a prospective cohort study.Annals of intensive care · 2024Article
- Health-related quality of life and participation after inpatient rehabilitation of sepsis survivors with severe sequelae: a cohort study.Journal of rehabilitation medicine · 2024Article
- Psychosocial and socioeconomic factors are most predictive of health status in patients with claudication.Journal of vascular surgery · 2024Article
- Balance function in critical illness survivors and evaluation of psychometric properties of the Mini-BESTest.Scientific reports · 2024Article
- Article
- Reduced health-related quality of life, fatigue, anxiety and depression affect COVID-19 patients in the long-term after chronic critical illness.Scientific reports · 2024Article
- Effectiveness of massage and range of motion exercises on muscle strength and intensive care unit-acquired weakness in Iranian patients with COVID-19: a randomized parallel-controlled trial.Acute and critical care · 2024Article
- Muscle strength/intensive care unit acquired weakness in COVID-19 and non-COVID-19 patients.Nursing in critical care · 2023Article
- Article
- Intensive Care Unit- Acquired Weakness and Hospital Functional Mobility Outcomes Following Invasive Mechanical Ventilation in Patients with COVID-19: A Single-Centre Prospective Cohort Study.Journal of intensive care medicine · 2022Article
- A randomized controlled clinical trial of the effects of range of motion exercises and massage on muscle strength in critically ill patients.BMC sports science, medicine & rehabilitation · 2022Article
- Sex-Specific Aspects of Skeletal Muscle Metabolism in the Clinical Context of Intensive Care Unit-Acquired Weakness.Journal of clinical medicine · 2022Article
- Mixed-method research protocol: Development and evaluation of a nursing intervention in patients discharged from the intensive care unit.Nursing open · 2021Article
- Article
- Impact of peripheral muscle strength on prognosis after extubation and functional outcomes in critically ill patients: a feasibility study.Scientific reports · 2021Observational
- Five-year impact of ICU-acquired neuromuscular complications: a prospective, observational study.Intensive care medicine · 2020Observational
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe predictors for health-related quality of life, participation, physical activity and cognitive function in patients with intensive care unit (ICU)-acquired muscle weakness 1 year after discharge from rehabilitation.
designThis is a cohort study.
participantsWe included 150 chronic critically ill individuals with ICU-acquired muscle weakness.
settingPostacute ICU and rehabilitation units in Germany. MEASURES: We measured health-related quality of life using the EQ-5D, participation using the Reintegration of Normal Living Index, physical activity using the Physical Activity Scale for Individuals With Physical Disabilities, and basal cognitive function using the Montreal Cognitive Assessment (MoCA) at 6 months, and the Clock Drawing Test 6 and 12 months after discharge from postacute treatment. We described the predictors of the results at 12 months.
resultsThe best predictors for good health-related quality of life 1 year after discharge were the time until regaining walking ability (OR=0.96, OR per day, 95% CI 0.93 to 0.99) and the mean MoCA score on admission to our postacute ICU and rehabilitation units (OR=1.25,95% CI 1.02 to 1.52).The best predictor for good participation 1 year after discharge was the MoCA sum score on admission to our postacute ICU and rehabilitation units (OR=0.85,95% CI 0.72 to 1.00). The best predictor for good physical activity 1 year after discharge was the Apache sum score on admission to our postacute ICU and rehabilitation units (OR=1.68,95% CI 0.89 to 3.13). The best predictor for normal cognitive function 1 year after discharge was regaining walking function in rehabilitation (OR=8.0,95% CI 0.49 to 13.69).
conclusionRecovery of health-related quality of life, participation, physical activity and basal cognitive function was still not complete 12 months after discharge from postacute treatment. We described the predictors for these important outcomes in participants with ICU-acquired muscle weakness 1 year after discharge from rehabilitation. TRIAL REGISTRATION NUMBER: DRKS00007181.
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