Evidence map›Paper›PMID 30007244›Full record

ReviewCurrent opinion in genetics & development2018

Dynamic interplay of cell fate, polarity and force generation in ascidian embryos.

Hidehiko Hashimoto, Edwin Munro

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in genetics & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Mechanical regulation of early vertebrate embryogenesis.Nature reviews. Molecular cell biology · 2022
    Review
  5. Review
  6. Article
  7. Physical constraints on early blastomere packings.PLoS computational biology · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Hidehiko HashimotoDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, United States. Electronic address: hhashimoto@uchicago.edu.
Edwin MunroDepartment of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, United States; Committee on Development, Regeneration and Stem Cell Biology, University of Chicago, Chicago, IL 60637, United States. Electronic address: emunro@uchicago.edu.
University of Chicago · US

Funding

Mechanistic origins and dynamic control of epithelial zippering and neural tube closureR01HD088831 · NICHD · UNIVERSITY OF CHICAGO · PI MUNRO, EDWIN MARSHALL · 2016 to 2020
$1.6M
NICHD NIH HHS R01 HD088831
6 · The paper itself

Abstract

A fundamental challenge in developmental biology is to understand how forces produced by individual cells are patterned in space and time and then integrated to produce stereotyped changes in tissue-level or embryo-level morphology. Ascidians offer a unique opportunity to address this challenge by studying how small groups of cells collectively execute complex, but highly stereotyped morphogenetic movements. Here we highlight recent progress and open questions in the study of ascidian morphogenesis, emphasizing the dynamic interplay of cell fate determination, cellular force generation and tissue-level mechanics.

Indexed as

AnimalsCell DifferentiationCell PolarityEmbryonic DevelopmentEmbryo, NonmammalianGene Expression Regulation, DevelopmentalMorphogenesisUrochordata

Identifiers

PMID30007244
PMCPMC6543843
OpenAlexW2837058045

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.