Evidence map›Paper›PMID 30006840›Full record

Observational studySurgical endoscopy2019

Self-expandable metallic stenting as a bridge to surgery for malignant colorectal obstruction: pooled analysis of 426 patients from two prospective multicenter series.

Masafumi Tomita, Shuji Saito, Shinichiro Makimoto, Shuntaro Yoshida, Hiroyuki Isayama, Tomonori Yamada, Takeaki Matsuzawa, Toshiyuki Enomoto, Rika Kyo, Toshio Kuwai and 5 more

Open access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Masafumi TomitaDepartment of Surgery, Kishiwada Tokushukai Hospital, 4-27-1 Kamori-cho, Kishiwada-shi, Osaka, 596-8522, Japan. mtomita@sc4.so-net.ne.jp.ORCID http://orcid.org/0000-0002-1654-4788
Shuji SaitoDivision of Surgery, Gastrointestinal Center, Yokohama Shin-Midori General Hospital, Yokohama, Japan.
Shinichiro MakimotoDepartment of Surgery, Kishiwada Tokushukai Hospital, 4-27-1 Kamori-cho, Kishiwada-shi, Osaka, 596-8522, Japan.
Shuntaro YoshidaDepartment of Endoscopy and Endoscopic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroyuki IsayamaDepartment of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.
Tomonori YamadaDepartment of Gastroenterology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Japan.
Takeaki MatsuzawaDepartment of Digestive and General Surgery, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan.
Toshiyuki EnomotoDepartment of Surgery, Toho University Ohashi Medical Center, Tokyo, Japan.
Rika KyoDepartment of Gastroenterology, Saiseikai Yokohamashi-Nanbu Hospital, Yokohama, Japan.
Toshio KuwaiDepartment of Gastroenterology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Kure, Japan.
Nobuto HirataDepartment of Gastroenterology, Kameda Medical Center, Kamogawa, Chiba, Japan.
Mamoru ShimadaDepartment of Surgery, Toyonaka Midorigaoka Hospital, Osaka, Japan.
Tomio HirakawaDepartment of Gastroenterology, Toyonaka Midorigaoka Hospital, Osaka, Japan.
Koichi KoizumiDepartment of Gastroenterology, Tokyo Metropolitan Cancer and Infectious Disease Center Komagome Hospital, Tokyo, Japan.
Yoshihisa SaidaDepartment of Surgery, Toho University Ohashi Medical Center, Tokyo, Japan.
Kishiwada Tokushukai Hospital · JPMidorigaoka Hospital · JPToho University · JPJapanese Red Cross Nagoya Daini Hospital · JPJuntendo University · JPKameda Medical Center · JPNational Hospital Organization · JPNiigata University Medical and Dental Hospital · JPThe University of Tokyo · JPTokyo Metropolitan Komagome Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-expandable metallic stenting (SEMS) for malignant colorectal obstruction (MCO) as a bridge to elective surgery (BTS) is a widely used procedure. The aim of this study was to assess short-term outcomes of SEMS for MCO as BTS.

methodsThis study analyzed pooled data from BTS patients who were enrolled in two multicenter prospective single-arm observational clinical studies that used different stent types. Both studies were conducted by the Japan Colonic Stent Safe Procedure Research Group (JCSSPRG). The first study evaluated the WallFlex™ colonic stent for BTS or palliative treatment (PAL) from May 2012 to October 2013 and the second evaluated the Niti-S™ colonic stent from October 2013 to May 2014. Fifty-three facilities in Japan participated in the studies. Before each study started, the procedure had been shared with the participating institutions by posting details of the standard methods of SEMS placement on the JCSSPRG website. Patients were followed until discharged after surgery.

resultsA total of 723 consecutive patients were enrolled in the two studies. After excluding nine patients, the remaining 714 patients were evaluated as a per-protocol cohort. SEMS placement was performed in 426 patients (312 WallFlex and 114 Niti-S) as BTS and in 288 as PAL. In the 426 BTS patients, the technical success rate was 98.1% (418/426). The clinical success rate was 93.8% (392/418). SEMS-related preoperative complications occurred in 8.5% of patients (36/426), perforations in 1.9% (8/426), and stent migration in 1.2% (5/426). Primary anastomosis was possible in 91.8% of patients (391/426), 3.8% of whom (15/393) had anastomosis leakage. The overall stoma creation rate was 10.6% (45/426). The postoperative complication rate was 16.9% (72/426) and mortality rate was 0.5% (2/426).

conclusionsSEMS placement for MCO as BTS is safe and effective with respect to peri-procedural outcomes. Further investigations are needed to confirm long-term oncological outcomes.

Indexed as

Self Expandable Metallic StentsAgedColorectal NeoplasmsElective Surgical ProceduresFeasibility StudiesFemaleHumansIntestinal ObstructionJapanMaleMiddle AgedPalliative CarePostoperative ComplicationsProspective StudiesBridge to surgeryColon and rectal cancerIntestinal obstructionMulticenter studyProspective cohort studySelf-expandable metallic stent

Identifiers

PMID30006840
PMCPMC6342866
OpenAlexW2884140524

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.