Evidence map›Paper›PMID 30006836›Full record

ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2018

Pyramiding of nine transgenes in maize generates high-level resistance against necrotrophic maize pathogens.

Xiang Zhu, Jinfeng Zhao, Hafiz Muhammad Khalid Abbas, Yunjun Liu, Menglan Cheng, Jue Huang, Wenjuan Cheng, Beibei Wang, Cuiying Bai, Guoying Wang and 1 more

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In one paragraph

Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Genetic dissection of maize disease resistance and its applications in molecular breeding.Molecular breeding : new strategies in plant improvement · 2021
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiang ZhuDepartment of Plant Pathology, College of Plant Science and Technology and the Key Lab of Crop Disease Monitoring and Safety Control in Hubei Province, Huazhong Agricultural University, Wuhan, 430070, Hubei Province, China.
Jinfeng ZhaoMillet Research Institute, Shanxi Academy of Agricultural Sciences, Changzhi, 046011, Shanxi Province, China.
Hafiz Muhammad Khalid AbbasDepartment of Plant Pathology, College of Plant Science and Technology and the Key Lab of Crop Disease Monitoring and Safety Control in Hubei Province, Huazhong Agricultural University, Wuhan, 430070, Hubei Province, China.
Yunjun LiuInstitute of Crop Science, Chinese Academy of Agricultural Sciences, South Street of Zhongguancun 12, Beijing, 100081, China.
Menglan ChengDepartment of Plant Pathology, College of Plant Science and Technology and the Key Lab of Crop Disease Monitoring and Safety Control in Hubei Province, Huazhong Agricultural University, Wuhan, 430070, Hubei Province, China.
Jue HuangDepartment of Plant Pathology, College of Plant Science and Technology and the Key Lab of Crop Disease Monitoring and Safety Control in Hubei Province, Huazhong Agricultural University, Wuhan, 430070, Hubei Province, China.
Wenjuan ChengDepartment of Plant Pathology, College of Plant Science and Technology and the Key Lab of Crop Disease Monitoring and Safety Control in Hubei Province, Huazhong Agricultural University, Wuhan, 430070, Hubei Province, China.
Beibei WangDepartment of Plant Pathology, College of Plant Science and Technology and the Key Lab of Crop Disease Monitoring and Safety Control in Hubei Province, Huazhong Agricultural University, Wuhan, 430070, Hubei Province, China.
Cuiying BaiDepartment of Plant Pathology, College of Plant Science and Technology and the Key Lab of Crop Disease Monitoring and Safety Control in Hubei Province, Huazhong Agricultural University, Wuhan, 430070, Hubei Province, China.
Guoying WangInstitute of Crop Science, Chinese Academy of Agricultural Sciences, South Street of Zhongguancun 12, Beijing, 100081, China.
Wubei DongDepartment of Plant Pathology, College of Plant Science and Technology and the Key Lab of Crop Disease Monitoring and Safety Control in Hubei Province, Huazhong Agricultural University, Wuhan, 430070, Hubei Province, China. dwb@mail.hzau.edu.cn.ORCID http://orcid.org/0000-0001-8513-8751

Funding

The Hubei Provincial Technology Innovation Program 2016ABA093The National Major Project for Transgenic Organism Breeding 2016ZX08003-001
6 · The paper itself

Abstract

Key message Nine transgenes from different categories, viz. plant defense response genes and anti-apoptosis genes, played combined roles in maize to inhibit the necrotrophic pathogens Rhizoctonia solani and Bipolaris maydis. Maize sheath blight and southern corn leaf blight are major global threats to maize production. The management of these necrotrophic pathogens has encountered limited success due to the characteristics of their lifestyle. Here, we presented a transgenic pyramiding breeding strategy to achieve nine different resistance genes integrated in one transgenic maize line to combat different aspects of necrotrophic pathogens. These nine genes, selected from two different categories, plant defense response genes (Chi, Glu, Ace-AMP1, Tlp, Rs-AFP2, ZmPROPEP1 and Pti4), and anti-apoptosis genes (Iap and p35), were successfully transferred into maize and further implicated in resistance against the necrotrophic pathogens Rhizoctonia solani and Bipolaris maydis. Furthermore, the transgenic maize line 910, with high expression levels of the nine integrated genes, was selected from 49 lines. Under greenhouse and field trial conditions, line 910 showed significant resistance against maize sheath blight and southern corn leaf blight diseases. Higher-level resistance was obtained after the pyramiding of more resistance transgenes from different categories that function via different mechanisms. The present study provides a successful strategy for the management of necrotrophic pathogens.

Indexed as

Plant BreedingTransgenesAscomycotaDisease ResistancePlant DiseasesPlants, Genetically ModifiedRhizoctoniaZea mays

Identifiers

PMID30006836

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.