Evidence map›Paper›PMID 30006784›Full record

ReviewApplied microbiology and biotechnology2018

Metabolic engineering for the production of isoprene and isopentenol by Escherichia coli.

Meijie Li, Rui Nian, Mo Xian, Haibo Zhang

Open access · hybridAbstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 76 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Systematic metabolic engineering ofFrontiers in bioengineering and biotechnology · 2024
    Article
  7. Optimization of IspSApplied and environmental microbiology · 2023
    Article
  8. Article
  9. Engineering a mevalonate pathway inFrontiers in microbiology · 2022
    Article
  10. Article
  11. Characteristics and Application ofFrontiers in bioengineering and biotechnology · 2022
    Review
  12. Microbial (Frontiers in bioengineering and biotechnology · 2022
    Review
  13. Positioning Bacillus subtilis as terpenoid cell factory.Journal of applied microbiology · 2021
    Review
  14. Metabolic EngineeringMolecules (Basel, Switzerland) · 2020
    Review
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Meijie LiKey Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 135 Songling Road, Qingdao, 266101, People's Republic of China.
Rui NianKey Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 135 Songling Road, Qingdao, 266101, People's Republic of China.
Mo XianKey Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 135 Songling Road, Qingdao, 266101, People's Republic of China. xianmo1@qibebt.ac.cn.
Haibo ZhangKey Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 135 Songling Road, Qingdao, 266101, People's Republic of China. zhanghb@qibebt.ac.cn.
Qingdao Institute of Bioenergy and Bioprocess Technology · CNUniversity of Chinese Academy of Sciences · CN

Funding

Hainan's Key Project of Research and Development Plan ZDYF2017155National Natural Science Foundation of China 31400084Taishan Scholars Climbing Program of Shandong TSPD20150210Youth Innovation Promotion Association CAS 2017252
6 · The paper itself

Abstract

The biotechnological production of isoprene and isopentenol has recently been studied. Isoprene, which is currently made mainly from petroleum, is an important platform chemical for synthesizing pesticides, medicines, oil additives, fragrances, and more and is especially important in the rubber production industry. Isopentenols, which have better combustion properties than well-known biofuels (ethanol), have recently received more attention. Supplies of petroleum, the conventional source of isoprene and isopentenols, are unsustainable, and chemical synthesis processes could cause serious environmental problems. As an alternative, the biosynthesis of isoprene and isopentenols in cell factories is more sustainable and environmentally friendly. With a number of advantages over other microorganisms, Escherichia coli is considered to be a powerful workhorse organism for producing these compounds. This review will highlight the recent advances in metabolic engineering for isoprene and isopentenol production, especially using E. coli cell factories.

Indexed as

Metabolic EngineeringAmino Acid SequenceButadienesEscherichia coliHemiterpenesPentanolsSequence Homology, Amino AcidButadienesHemiterpenesisopentenolisoprenePentanolsIsopentenolIsopreneMEPMetabolic engineeringMVA

Identifiers

PMID30006784
PMCPMC6132537
OpenAlexW2884433046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.