Evidence map›Paper›PMID 30006584›Full record

ArticleInternational journal of obesity (2005)2019

Maternal pre-pregnancy obesity and health care utilization and costs in the offspring.

Stefan Kuhle, Adam Muir, Christy G Woolcott, Mary M Brown, Sarah D McDonald, Mohamed Abdolell, Linda Dodds

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in International journal of obesity (2005), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05754645 (The PROMOTE Study, a Pilot), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05754645 recruitingnot on this mapstarted 2022, after this paper: background citation

The PROMOTE Study, a Pilot: The Characterization of the Microbiome in Pregnancy and Prediction of Pregnancy Outcomes

TypeobservationalSponsorErasmus Medical CenterRan2022 to 2026Enrolled110ConditionsObesity, Maternal, Pregnancy Complications, Gut MicrobiotaArmsBlood withdrawal
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  6. Review
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  11. Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stefan KuhleDepartments of Obstetrics & Gynaecology and Pediatrics, Perinatal Epidemiology Research Unit, Dalhousie University, Halifax, NS, Canada. stefan.kuhle@dal.ca.ORCID http://orcid.org/0000-0001-9417-3727
Adam MuirDepartments of Obstetrics & Gynaecology and Pediatrics, Perinatal Epidemiology Research Unit, Dalhousie University, Halifax, NS, Canada.
Christy G WoolcottDepartments of Obstetrics & Gynaecology and Pediatrics, Perinatal Epidemiology Research Unit, Dalhousie University, Halifax, NS, Canada.
Mary M BrownDepartments of Obstetrics & Gynaecology and Pediatrics, Perinatal Epidemiology Research Unit, Dalhousie University, Halifax, NS, Canada.
Sarah D McDonaldDepartment of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, McMaster University, Hamilton, ON, Canada.
Mohamed AbdolellDepartment of Diagnostic Radiology, Dalhousie University, Halifax, NS, Canada.
Linda DoddsDepartments of Obstetrics & Gynaecology and Pediatrics, Perinatal Epidemiology Research Unit, Dalhousie University, Halifax, NS, Canada.
Dalhousie University · CAImpact · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveThe association between maternal pre-pregnancy obesity and adverse child health outcomes is well described, but there are few data on the relationship with offspring health service use. We examined the influence of maternal pre-pregnancy obesity on offspring health care utilization and costs over the first 18 years of life.

methodsThis was a population-based retrospective cohort study of children (n = 35,090) born between 1989 and 1993 and their mothers, who were identified using the Nova Scotia Atlee Perinatal Database and linked to provincial administrative health data from birth through 2014. The primary outcome was health care utilization as determined by the number and cost of physician visits, hospital admissions and days, and high utilizer status (>95th percentile of physician visits). The secondary outcome was health care utilization by ICD chapter. Maternal pre-pregnancy weight was categorized as normal weight, overweight, or obese. Multivariable-adjusted regression models were used to examine the association between maternal weight status and offspring health care use.

resultsChildren of mothers with pre-pregnancy obesity had more physician visits (10%), hospital admissions (16%), and hospital days (10%) than children from mothers of normal weight over the first 18 years of life. Offspring of mothers with obesity had C$356 higher physician costs and C$1415 hospital costs over 18 years than offspring of normal weight mothers. Children of mothers with obesity were 1.74 times more likely to be a high utilizer of health care and had higher rates of physician visits and hospital stays for nervous system and sense organ disorders, respiratory disorders, and gastrointestinal disorders compared to children of normal weight mothers.

conclusionOur findings suggest that maternal pre-pregnancy overweight and obesity are associated with slightly higher offspring health care utilization and costs in the first 18 years of life.

Indexed as

MothersAdolescentAdultBody Mass IndexChildChild DevelopmentChild, PreschoolFemaleHealth SurveysHumansInfantInfant, NewbornMaleNova ScotiaObesityPatient Acceptance of Health Care

Identifiers

PMID30006584
PMCPMC6484728
OpenAlexW2884312652

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.