Evidence map›Paper›PMID 30006567›Full record

ArticleScientific reports2018

Fate of mesoangioblasts in a vaginal birth injury model: influence of the route of administration.

Marina Gabriela Monteiro Carvalho Mori da Cunha, Giorgia Giacomazzi, Geertje Callewaert, Lucie Hympanova, Francesca Russo, Greetje Vande Velde, Rik Gijsbers, Maarten Albersen, Maurilio Sampaolesi, Jan Deprest

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Chapter 4.5: New Proposed Treatments for Pelvic Organ Prolapse.International urogynecology journal · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Stem cell therapy for muscular dystrophies.The Journal of clinical investigation · 2020
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Marina Gabriela Monteiro Carvalho Mori da CunhaCentre for Surgical Technologies, Group Biomedical Sciences, KU Leuven, Leuven, Belgium.
Giorgia GiacomazziTranslational Cardiomyology Lab, Stem Cell Biology and Embryology Unit, Department Development and Regeneration, KU Leuven, Leuven, Belgium.
Geertje CallewaertCentre for Surgical Technologies, Group Biomedical Sciences, KU Leuven, Leuven, Belgium.
Lucie HympanovaCentre for Surgical Technologies, Group Biomedical Sciences, KU Leuven, Leuven, Belgium.
Francesca RussoCentre for Surgical Technologies, Group Biomedical Sciences, KU Leuven, Leuven, Belgium.
Greetje Vande VeldeMolecular Small Animal Imaging Center, KU Leuven, 3000, Leuven, Belgium.ORCID 0000-0002-5633-3993
Rik GijsbersLaboratory for Molecular Virology and Gene Therapy, KU Leuven, Flanders, Belgium.
Maarten AlbersenDepartment of Urology, University Hospitals Leuven, Leuven, Belgium.
Maurilio SampaolesiTranslational Cardiomyology Lab, Stem Cell Biology and Embryology Unit, Department Development and Regeneration, KU Leuven, Leuven, Belgium.
Jan DeprestCentre for Surgical Technologies, Group Biomedical Sciences, KU Leuven, Leuven, Belgium. jan.deprest@uzleuven.be.
KU Leuven · BECharles University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently cell therapy is considered as an experimental strategy to assist the healing process following simulated vaginal birth injury in rats, boosting the functional and morphologic recovery of pelvic floor muscles and nerves. However, the optimal administration route and dose still need to be determined. Mesangioblasts theoretically have the advantage that they can differentiate in skeletal and smooth muscle. We investigated the fate of mesoangioblasts transduced with luciferase and green fluorescent protein reporter genes (rMABs

Indexed as

Wound HealingAnimalsCells, CulturedDelivery, ObstetricFemaleGenetic VectorsGreen Fluorescent ProteinsInjections, Intra-ArterialInjections, IntralesionalInjections, IntravenousIntravital MicroscopyLuciferases, FireflyMesenchymal Stem Cell TransplantationMicroscopy, FluorescencePregnancyPrimary Cell CultureGreen Fluorescent ProteinsLuciferases, Firefly

Identifiers

PMID30006567
PMCPMC6045600
OpenAlexW2823116190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.