Evidence map›Paper›PMID 30006490›Full record

ArticleJournal of the American Heart Association2018

Coronary Plaque Characteristics in Patients With Diabetes Mellitus Who Presented With Acute Coronary Syndromes.

Tomoyo Sugiyama, Erika Yamamoto, Krzysztof Bryniarski, Lei Xing, Francesco Fracassi, Hang Lee, Ik-Kyung Jang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01110538 (The Massachusetts General Hospital Optical Coherence Tomography Registry), which is not on this map. Cited by 47 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 3 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01110538 completednot on this map

The Massachusetts General Hospital Optical Coherence Tomography Registry

TypeobservationalSponsorIk-Kyung Jang, MD, PhDRan2010 to 2019Enrolled2,714ConditionsCoronary Artery Disease
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Drug-coated balloons and diabetes: a review.Cardiovascular diabetology · 2025
    Review
  13. Article
  14. Article
  15. Predictors of Five-Year Outcomes in Patients with Acute Coronary Syndromes.Journal of cardiovascular development and disease · 2025
    Article
  16. Revascularization in Diabetic Patients With Non-ST-Elevation Acute Myocardial Infarction.Mayo Clinic proceedings. Innovations, quality & outcomes · 2025
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Tomoyo SugiyamaCardiology Division, Massachusetts General Hospital Harvard Medical School, Boston, MA.
Erika YamamotoCardiology Division, Massachusetts General Hospital Harvard Medical School, Boston, MA.
Krzysztof BryniarskiCardiology Division, Massachusetts General Hospital Harvard Medical School, Boston, MA.
Lei XingCardiology Division, Massachusetts General Hospital Harvard Medical School, Boston, MA.
Francesco FracassiCardiology Division, Massachusetts General Hospital Harvard Medical School, Boston, MA.
Hang LeeBiostatistics Center, Massachusetts General Hospital Harvard Medical School, Boston, MA.
Ik-Kyung JangCardiology Division, Massachusetts General Hospital Harvard Medical School, Boston, MA ijang@mgh.harvard.edu.
Massachusetts General Hospital · USHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus (DM) is a major risk factor for cardiovascular events. We aimed to investigate the coronary plaque phenotype of diabetic patients who presented with acute coronary syndromes by optical coherence tomography. METHODS AND

resultsA total of 322 patients with acute coronary syndromes who underwent preintervention optical coherence tomography imaging of the culprit lesion were included. Culprit plaque characteristics were compared between patients with DM (n=95) and those without DM (n=227). In the subgroup of 250 patients in whom sufficient length of nonculprit region in the culprit vessel was imaged by optical coherence tomography, the characteristics of nonculprit plaques were also evaluated. Patients with DM had a higher prevalence of lipid-rich plaque (58.9% versus 44.9%,

conclusionsCompared with patients without DM, those with DM had more vulnerable features in both culprit and nonculprit lesions, thus indicating a higher level of panvascular instability. CLINICAL

trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT01110538.

Indexed as

Acute Coronary SyndromeCoronary AngiographyCoronary VesselsDiabetes MellitusFemaleFollow-Up StudiesHumansMaleMiddle AgedPlaque, AtheroscleroticRegistriesRetrospective StudiesTomography, Optical Coherenceacute coronary syndromediabetes mellitusoptical coherence tomographyplaque

Identifiers

PMID30006490
PMCPMC6064844
OpenAlexW2884018942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.