Evidence map›Paper›PMID 30006462›Full record

ArticleThe Journal of cell biology2018

The force-sensitive protein Ajuba regulates cell adhesion during epithelial morphogenesis.

William Razzell, Maria E Bustillo, Jennifer A Zallen

Abstract read
In one paragraph

Article in The Journal of cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 72 citations in OpenAlex.

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  6. International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

William RazzellHoward Hughes Medical Institute and Developmental Biology Program, Sloan Kettering Institute, New York, NY.ORCID 0000-0002-1262-0501
Maria E BustilloHoward Hughes Medical Institute and Developmental Biology Program, Sloan Kettering Institute, New York, NY.ORCID 0000-0001-5754-0970
Jennifer A ZallenHoward Hughes Medical Institute and Developmental Biology Program, Sloan Kettering Institute, New York, NY zallenj@mskcc.org.ORCID 0000-0003-3975-1568
Howard Hughes Medical Institute · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Training Program in Developmental BiologyT32HD060600 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI BAO, ZHIRONG, STUHLMANN, HEIDI · 2010 to 2024
$3.5M
Biophysical Mechanisms of Drosophila Development.R01GM102803 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI ZALLEN, JENNIFER A · 2012 to 2015
$1.1M
Howard Hughes Medical InstituteNCI NIH HHS P30 CA008748NICHD NIH HHS T32 HD060600NIGMS NIH HHS R01 GM102803
6 · The paper itself

Abstract

The reorganization of cells in response to mechanical forces converts simple epithelial sheets into complex tissues of various shapes and dimensions. Epithelial integrity is maintained throughout tissue remodeling, but the mechanisms that regulate dynamic changes in cell adhesion under tension are not well understood. In

Indexed as

ActomyosinAdherens JunctionsAnimalsCell AdhesionDrosophila melanogasterDrosophila ProteinsEpitheliumLIM Domain ProteinsMorphogenesisProtein DomainsActomyosinDrosophila Proteinsjub protein, DrosophilaLIM Domain Proteins

Identifiers

PMID30006462
PMCPMC6168262
OpenAlexW2884974871

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.