Evidence map›Paper›PMID 30006429›Full record

GuidelineJournal of the National Comprehensive Cancer Network : JNCCN2018

Rectal Cancer, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.

Al B Benson, Alan P Venook, Mahmoud M Al-Hawary, Lynette Cederquist, Yi-Jen Chen, Kristen K Ciombor, Stacey Cohen, Harry S Cooper, Dustin Deming, Paul F Engstrom and 25 more

Abstract readPractice Guideline
In one paragraph

Guideline in Journal of the National Comprehensive Cancer Network : JNCCN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 488 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
488citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

488 citing papers in PubMed, 14 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Guideline
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  12. Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2023
    Guideline
  13. Pooled it
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  15. Trial
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428 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Al B Benson
Alan P Venook
Mahmoud M Al-Hawary
Lynette Cederquist
Yi-Jen Chen
Kristen K Ciombor
Stacey Cohen
Harry S Cooper
Dustin Deming
Paul F Engstrom
Jean L Grem
Axel Grothey
Howard S Hochster
Sarah Hoffe
Steven Hunt
Ahmed Kamel
Natalie Kirilcuk
Smitha Krishnamurthi
Wells A Messersmith
Jeffrey Meyerhardt
Mary F Mulcahy
James D Murphy
Steven Nurkin
Leonard Saltz
Sunil Sharma
David Shibata
John M Skibber
Constantinos T Sofocleous
Elena M Stoffel
Eden Stotsky-Himelfarb
Christopher G Willett
Evan Wuthrick
Kristina M Gregory
Lisa Gurski
Deborah A Freedman-Cass

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Rectal Cancer address diagnosis, staging, surgical management, perioperative treatment, management of recurrent and metastatic disease, disease surveillance, and survivorship in patients with rectal cancer. This portion of the guidelines focuses on the management of localized disease, which involves careful patient selection for curative-intent treatment options that sequence multimodality therapy usually comprised of chemotherapy, radiation, and surgical resection.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsBiopsyChemoradiotherapyDisease-Free SurvivalHumansIncidenceInduction ChemotherapyMedical OncologyNeoadjuvant TherapyNeoplasm Recurrence, LocalNeoplasm StagingPatient SelectionProctectomyRandomized Controlled Trials as TopicRectal NeoplasmsRectum

Identifiers

PMID30006429
PMCPMC10203817

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.