Evidence map›Paper›PMID 30006414›Full record

ArticleGenome research2018

Variant antigen repertoires in

Sara Silva Pereira, Aitor Casas-Sánchez, Lee R Haines, Moses Ogugo, Kihara Absolomon, Mandy Sanders, Steve Kemp, Álvaro Acosta-Serrano, Harry Noyes, Matthew Berriman and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Sara Silva PereiraDepartment of Infection Biology, Institute of Infection and Global Health, University of Liverpool, Liverpool L3 5RF, United Kingdom.ORCID 0000-0002-6590-6626
Aitor Casas-SánchezDepartment of Parasitology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.ORCID 0000-0001-5237-1223
Lee R HainesDepartment of Vector Biology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Moses OgugoInternational Livestock Research Institute, Nairobi 00100, Kenya.
Kihara AbsolomonInternational Livestock Research Institute, Nairobi 00100, Kenya.
Mandy SandersWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1SA, United Kingdom.
Steve KempInternational Livestock Research Institute, Nairobi 00100, Kenya.
Álvaro Acosta-SerranoDepartment of Parasitology, Liverpool School of Tropical Medicine, Liverpool L3 5QA, United Kingdom.
Harry NoyesInstitute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, United Kingdom.
Matthew BerrimanWellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1SA, United Kingdom.
Andrew P JacksonDepartment of Infection Biology, Institute of Infection and Global Health, University of Liverpool, Liverpool L3 5RF, United Kingdom.
International Livestock Research Institute · KELiverpool School of Tropical Medicine · GBUniversity of Liverpool · GBWellcome Sanger Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M022811/1Wellcome TrustWellcome Trust WT098051
6 · The paper itself

Abstract

African trypanosomes are vector-borne hemoparasites of humans and animals. In the mammal, parasites evade the immune response through antigenic variation. Periodic switching of the variant surface glycoprotein (VSG) coat covering their cell surface allows sequential expansion of serologically distinct parasite clones. Trypanosome genomes contain many hundreds of

Indexed as

Polymorphism, GeneticAmino Acid MotifsAnimalsMaleSequence Analysis, DNATrypanosoma congolenseTsetse FliesVariant Surface Glycoproteins, TrypanosomaVariant Surface Glycoproteins, Trypanosoma

Identifiers

PMID30006414
PMCPMC6120623
OpenAlexW2884934870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.