ArticleVeterinary research2018
Control measures to prevent the increase of paratuberculosis prevalence in dairy cattle herds: an individual-based modelling approach.
Article in Veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Paratuberculosis control strategies in dairy cattle: A systematic review.Open veterinary journalPooled it
- Evaluation of the Johne's disease surveillance program in dairy herds in Hokkaido, Japan, using a stochastic individual-based simulation model.The Journal of veterinary medical science · 2026Article
- Age-structured next generation matrix and RInfectious Disease Modelling · 2026Article
- Use of ELISA to predict highJournal of veterinary research · 2026Article
- Johne's Disease Control in Beef Cattle: Balancing Test-and-Cull Strategies with Economic and Epidemiological Trade-Offs.Veterinary sciences · 2025Article
- MicroRNA-mediated regulatory mechanisms in cow's ileum and ileum lymph node in response to Mycobacterium avium subspecies paratuberculosis infection.Scientific reports · 2025Article
- Clinical insights on paratuberculosis in Arabian camels (Open veterinary journal · 2025Review
- When is the best time to test paratuberculosis positivity? Observations from a follow-up study in Hungarian dairy herds.Frontiers in veterinary science · 2025Article
- Rewiring cattle movements to limit infection spread.Veterinary research · 2024Article
- Comparison of Machine Learning Tree-Based Algorithms to Predict Future Paratuberculosis ELISA Results Using Repeat Milk Tests.Animals : an open access journal from MDPI · 2024Article
- Successful Control ofAnimals : an open access journal from MDPI · 2024Article
- Modelling transmission of Mycobacterium avium subspecies paratuberculosis between Irish dairy cattle herds.Veterinary research · 2022Article
- Effective Control of Johne's Disease in Large Czech Dairy Herds.Journal of veterinary research · 2022Article
- Investigating effective testing strategies for the control of Johne's disease in western Canadian cow-calf herds using an agent-based simulation model.Frontiers in veterinary science · 2022Article
- The Occurrence ofAnimals : an open access journal from MDPI · 2021Article
- Development and Validation of a Novel ELISA for the Specific Detection of Antibodies againstVeterinary medicine international · 2021Article
- Control of paratuberculosis: who, why and how. A review of 48 countries.BMC veterinary research · 2019Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paratuberculosis, a gastrointestinal disease caused by Mycobacterium avium subsp. paratuberculosis (Map), can lead to severe economic losses in dairy cattle farms. Current measures are aimed at controlling prevalence in infected herds, but are not fully effective. Our objective was to determine the most effective control measures to prevent an increase in adult prevalence in infected herds. We developed a new individual-based model coupling population and infection dynamics. Animals are characterized by their age (6 groups) and health state (6 states). The model accounted for all transmission routes and two control measures used in the field, namely reduced calf exposure to adult faeces and test-and-cull. We defined three herd statuses (low, moderate, and high) based on realistic prevalence ranges observed in French dairy cattle herds. We showed that the most relevant control measures depend on prevalence. Calf management and test-and-cull both were required to maximize the probability of stabilizing herd status. A reduced calf exposure was confirmed to be the most influential measure, followed by test frequency and the proportion of infected animals that were detected and culled. Culling of detected high shedders could be delayed for up to 3 months without impacting prevalence. Management of low prevalence herds is a priority since the probability of status stabilization is high after implementing prioritized measures. On the contrary, an increase in prevalence was particularly difficult to prevent in moderate prevalence herds, and was only feasible in high prevalence herds if the level of control was high.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.