Evidence map›Paper›PMID 30005663›Full record

Observational studyBMC public health2018

Effectiveness of an "Exclusive Intervention Strategy" to increase medical male circumcision uptake among men aged 25-49 years in South Africa.

Jonathan M Grund, Candice M Chetty-Makkan, Sibuse Ginindza, Reuben Munyai, Helen Kisbey-Green, Mpho Maraisane, Salome Charalambous

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02352961 (An Implementation Science Study Investigating Profiles of Men Interested in Medical Male Circumcision), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02352961 completednot on this map

An Implementation Science Study Investigating Profiles of Men Interested in Medical Male Circumcision (MMC), Barriers and Methods to Increase the Uptake of MMC Among Older Men in South Africa

TypeobservationalSponsorThe Aurum Institute NPCRan2014 to 2015Enrolled2,817ConditionsMedical Male CircumcisionArmsExclusive Intervention Strategy
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathan M GrundCenters for Disease Control and Prevention, 1600 Clifton Road NE, MS-E04, Atlanta, GA, 30333, USA. jgrund@cdc.gov.ORCID 0000-0002-1342-9813
Candice M Chetty-MakkanThe Aurum Institute, Johannesburg, Gauteng Province, South Africa.
Sibuse GinindzaThe Aurum Institute, Johannesburg, Gauteng Province, South Africa.
Reuben MunyaiThe Aurum Institute, Johannesburg, Gauteng Province, South Africa.
Helen Kisbey-GreenThe Aurum Institute, Johannesburg, Gauteng Province, South Africa.
Mpho MaraisaneThe Aurum Institute, Johannesburg, Gauteng Province, South Africa.
Salome CharalambousThe Aurum Institute, Johannesburg, Gauteng Province, South Africa.

Funding

CGH CDC HHS 5U01GH00522CGH CDC HHS U01 GH000522
6 · The paper itself

Abstract

backgroundSouth Africa introduced medical male circumcision (MMC) to reduce HIV incidence. Mathematical modeling suggested that targeting MMC services to men aged 20-34 years could provide the most immediate impact on HIV incidence. However the majority of MMCs performed have been among males aged ≤25 years. We evaluated an intervention package to increase MMC uptake among men aged 25-49 years.

methodsWe conducted a pre-post study to compare the proportion of men (aged 25-49 years) presenting for MMC during the formative (Phase 1) and intervention (Phase 2) phases in Ekurhuleni, Johannesburg, South Africa. The intervention included infrastructure changes that separated adults from adolescents at the MMC site, an exclusive men's health club, adult-specific demand generation materials, and discussions with community members.

resultsOverall 2817 enrolled in the study with 1601 from Phase 1 and 1216 in Phase 2. A higher proportion of participants aged 25-49 years accessed MMC in Phase 2 compared to Phase 1 (59.4% vs. 54.9%; Prevalence Ratio = 1.08; 95% Confidence Interval: 1.01-1.15; p = 0.019). Participants with multiple partners in the past 12 months in Phase 2 were more likely to access MMC services compared to participants in Phase 1 (unadjusted Odds Ratio, 1.37; 95% CI:1.17-1.61; p < 0.001). After adjusting for age, multiple partners remained a risk factor in Phase 2 (adjusted OR, 1.39; 95% CI: 1.18-1.63; p < 0.001).

conclusionsThe "Exclusive Intervention Strategy" was associated with a slight increase in the proportion of participants aged 25-49 years accessing MMC services, and an increase in those with HIV risk behaviors, during the intervention phase. These findings may provide important insights to overcoming barriers for accessing MMC services among men aged 25-49 years.

trial registrationThe study is registered at ClinicalTrials.gov , number NCT02352961 .

Indexed as

AdultCircumcision, MaleHIV InfectionsHumansIncidenceMaleMiddle AgedModels, TheoreticalProgram EvaluationRisk-TakingSexual PartnersSouth AfricaDemand creationHIV preventionMale circumcisionSouth Africa

Identifiers

PMID30005663
PMCPMC6044089

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.