Evidence map›Paper›PMID 30005654›Full record

ArticleBMC public health2018

Effect, process, and economic evaluation of a combined resistance exercise and diet intervention (ProMuscle in Practice) for community-dwelling older adults: design and methods of a randomised controlled trial.

Ellen J I van Dongen, Annemien Haveman-Nies, Nick L W Wezenbeek, Berber G Dorhout, Esmée L Doets, Lisette C P G M de Groot

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Strength Training and Nutrition Help Prevent Sarcopenia in Older Adults.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ellen J I van DongenFood, Health & Consumer Research, Wageningen Food & Biobased Research, P.O. Box 17, 6700 AA, Wageningen, The Netherlands. Ellen.vandongen@wur.nl.ORCID 0000-0002-5539-6570
Annemien Haveman-NiesDivision of Strategic Communication, Wageningen University and Research, P.O. Box 17, 6700 AA, Wageningen, The Netherlands.
Nick L W WezenbeekDivision of Human Nutrition, Wageningen University and Research, P.O. Box 17, 6700 AA, Wageningen, The Netherlands.
Berber G DorhoutDivision of Human Nutrition, Wageningen University and Research, P.O. Box 17, 6700 AA, Wageningen, The Netherlands.
Esmée L DoetsFood, Health & Consumer Research, Wageningen Food & Biobased Research, P.O. Box 17, 6700 AA, Wageningen, The Netherlands.
Lisette C P G M de GrootDivision of Human Nutrition, Wageningen University and Research, P.O. Box 17, 6700 AA, Wageningen, The Netherlands.
Wageningen University & Research · NLGGD Zuid Limburg · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExercise and nutrition are important for older adults to maintain or to regain their muscle mass, function, strength, and ultimately quality of life. The effectiveness of combined resistance exercise and diet interventions is commonly evaluated in controlled clinical studies, but evidence from real-life settings is lacking. This article describes the effectiveness, process, and economic evaluation design of a combined nutrition and exercise intervention for community-dwelling older adults in a Dutch real-life setting.

methodsThe ProMuscle in Practice study is a randomised controlled multicentre intervention study, conducted in five municipalities in the Netherlands. Two hundred community-dwelling older adults (≥65 years) who are frail or pre-frail based on Fried frailty criteria or who experience strength loss are randomised over an intervention and control group by municipality. In the first 12-week intensive support intervention, participants in the intervention group perform resistance exercise training guided by a physiotherapist twice a week and increase protein intake by consuming protein-rich products under the supervision of a dietitian. Afterwards, they continue with a 12-week moderate support intervention. The control group receives only regular care during the two 12-week periods. Effect outcomes are measured at all locations at baseline, 12 weeks, 24 weeks, 36 weeks and only at three locations at 52 weeks. The primary outcome is physical functioning (Short Physical Performance Battery). Secondary outcomes include leg muscle strength, lean body mass, activities of daily living, social participation, food intake, and quality of life. Qualitative and quantitative implementation process data are collected during the intervention. Healthcare use and intervention costs are registered for the economic evaluation. DISCUSSION: Evaluating the effects, implementation, and costs of this combined intervention provides valuable insight into the feasibility of this intervention for community-dwelling older adults and into the intervention's ability to improve or to maintain physical functioning and quality of life.

trial registrationNetherlands Trial Register ( NTR6038 ) since 30 August 2016.

Indexed as

DietAgedCost-Benefit AnalysisFemaleFrailtyHealth PromotionHumansIndependent LivingMaleMulticenter Studies as TopicNetherlandsProgram EvaluationQuality of LifeRandomized Controlled Trials as TopicResearch DesignResistance TrainingCommunity-dwelling older adultsDietary protein intakeEvaluationPhysical functioningReal-life settingResistance exerciseSarcopenia

Identifiers

PMID30005654
PMCPMC6045872
OpenAlexW2884033867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.