Evidence map›Paper›PMID 30005643›Full record

Trial reportBMC public health2018

Effectiveness of peer support to increase uptake of retinal examination for diabetic retinopathy: study protocol for the DURE pragmatic cluster randomized clinical trial in Kirinyaga, Kenya.

Nyawira Mwangi, Mark Ng'ang'a, Esbon Gakuo, Stephen Gichuhi, David Macleod, Consuela Moorman, Lawrence Muthami, Peter Tum, Atieno Jalango, Kibata Githeko and 4 more

Open access · goldAbstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in BMC public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Nyawira MwangiKenya Medical Training College, Nairobi, Kenya. Nyawira.Mwangi@lshtm.ac.uk.ORCID 0000-0002-8236-470X
Mark Ng'ang'aKerugoya County Referral Hospital, Kerugoya, Kenya.
Esbon GakuoKirinyaga County Health Services, Kerugoya, Kenya.
Stephen GichuhiDepartment of Ophthalmology, University of Nairobi, Nairobi, Kenya.
David MacleodInternational Centre for Eye Health, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK.
Consuela MoormanOxford University Hospitals NHS Trust, Oxford, UK.
Lawrence MuthamiKenya Medical Research Institute, Nairobi, Kenya.
Peter TumKenya Medical Training College, Nairobi, Kenya.
Atieno JalangoKabarak University, Nakuru, Kenya.
Kibata GithekoUpper Hill Eye and Laser Centre, Nairobi, Kenya.
Michael GichangiOphthalmic Services Unit, Ministry of Health, Nairobi, Kenya.
Joseph KibachioDivision of Non-Communicable Diseases, Ministry of Health, Nairobi, Kenya.
Covadonga BascaranInternational Centre for Eye Health, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK.
Allen FosterInternational Centre for Eye Health, London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK.
London School of Hygiene & Tropical Medicine · GBKenya Medical Training College · KEKirinyaga University · KEMinistry of Health · KEKabarak University · KEKenya Medical Research Institute · KEOxford University Hospitals NHS Trust · GBUniversity of Nairobi · KE

Funding

Medical Research Council MR/K012126/1
6 · The paper itself

Abstract

backgroundAll patients with diabetes are at risk of developing diabetic retinopathy (DR), a progressive and potentially blinding condition. Early treatment of DR prevents visual impairment and blindness. The natural history of DR is that it is asymptomatic until the advanced stages, thus annual retinal examination is recommended for early detection. Previous studies show that the uptake of regular retinal examination among people living with diabetes (PLWD) is low. In the Uptake of Retinal Examination in Diabetes (DURE) study, we will investigate the effectiveness of a complex intervention delivered within diabetes support groups to increase uptake of retinal examination.

methodsThe DURE study will be a two-arm pragmatic cluster randomized clinical trial in Kirinyaga County, Kenya. Diabetes support groups will be randomly assigned to either the intervention or usual care conditions in a 1:1 ratio. The participants will be 700 PLWD who are members of support groups in Kirinyaga. To reduce contamination, the unit of randomization will be the support group. Peer supporters in the intervention arm will receive training to deliver the intervention. The intervention will include monthly group education on DR and individual member reminders to take the eye examination. The effectiveness of this intervention plus usual care will be compared to usual care practices alone. Participant data will be collected at baseline. The primary outcome is the proportion of PLWD who take up the eye examination at six months. Secondary outcomes include the characteristics of participants and peer supporters associated with uptake of eye examination for DR. Intention-to-treat analysis will be used to evaluate the primary and secondary outcomes. DISCUSSION: Eye care programs need evidence of the effectiveness of peer supporter-led health education to improve attendance to retinal screening for the early detection of DR in an African setting. Given that the intervention combines standardization and flexibility, it has the potential to be adopted in other settings and to inform policies to promote DR screening.

trial registrationPan African Clinical Trial Registry PACTR201707002430195 , registered 25 July 2017, www.pactr.org.

Indexed as

Peer InfluenceSelf-Help GroupsAdolescentAdultDiabetic RetinopathyFemaleHealth EducationHumansKenyaMaleMass ScreeningPhysical ExaminationResearch DesignAfricaBlindnessDiabetes mellitusDiabetes support groupsDiabetic retinopathyHealth educationKenyaPeer-supportRetinal screeningSelf-efficacy theory

Identifiers

PMID30005643
PMCPMC6044026
OpenAlexW2883548430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.