ArticleRespiratory research2018
Cryobiopsies are diagnostic in Pleuroparenchymal and Airway-centered Fibroelastosis.
Article in Respiratory research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Quantitative assessment of fibroelastosis reveals distinct elastic and collagen fiber patterns in idiopathic and secondary pleuroparenchymal fibroelastosis.Virchows Archiv : an international journal of pathology · 2026Article
- Korean Guidelines for the Diagnosis and Management of Interstitial Lung Disease: Other Forms of Interstitial Lung Disease.Tuberculosis and respiratory diseases · 2025Article
- Article
- Multidisciplinary Approach to the Diagnosis of Idiopathic Interstitial Pneumonias: Focus on the Pathologist's Key Role.International journal of molecular sciences · 2024Review
- Two cases of airway-centered fibroelastosis treated with an antifibrotic agent and corticosteroids.Respiratory medicine case reports · 2024Article
- The world of rare interstitial lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2023Review
- Pleuroparenchymal Fibroelastosis with a Predominantly Airway-centered Distribution: A Late Complication of Chemotherapy.Internal medicine (Tokyo, Japan) · 2022Article
- Pulmonary Fibroelastotic Remodelling Revisited.Cells · 2021Article
- The pathogenesis and pathology of idiopathic pleuroparenchymal fibroelastosis.Histology and histopathology · 2021Review
- Pleuroparenchymal fibroelastosis in systemic sclerosis: prevalence and prognostic impact.The European respiratory journal · 2020Article
- Pleuroparenchymal Fibroelastosis. A Review of Clinical, Radiological, and Pathological Characteristics.Annals of the American Thoracic Society · 2019Review
- Pleuroparenchymal fibroelastosis (PPFE) treated with lung transplantation and review of the literature.BMJ case reports · 2019Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIdiopathic pulmonary fibroelastosis (iPPFE) is a rare lung lesion characterized by pleural and subpleural parenchymal thickening due to accumulation of fibroelastotic tissue. Only recently, a few cases with a peribronchiolar distribution of fibroelastotic tissue have been reported. These lesions are more prominent in the upper lobes. Even though high resolution computed tomography (HRCT) scan features are considered characteristic, a histological confirmation is suggested, mainly when the clinical setting is not clearly defined. However, due to non-negligible complications, a surgical lung biopsy is not often recommended. The prognosis is usually poor and currently, the only effective treatment is lung transplantation.
methodPatients with a multidisciplinary diagnosis of iPPFE or airway-centered fibroelastosis (airway-centered FE), with histological confirmation by transbronchial cryobiopsy, were identified from an ongoing interstitial lung disease registry. Data on patient demographics, HRCT patterns, size and number of biopsies, histology patterns and complications were registered.
resultsSeven patients were diagnosed with iPPFE and one patient was diagnosed with airway-centered FE. Pneumothorax was documented in three cases, but none of them required a chest tube. No other complications during or after the procedure were observed.
conclusionThis study suggests that using cryobiopsies in the diagnostics of PPFE and airway-centered FE is safe and effective.
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