Evidence map›Paper›PMID 30005602›Full record

ArticleBMC genomics2018

Wolf outside, dog inside? The genomic make-up of the Czechoslovakian Wolfdog.

Romolo Caniglia, Elena Fabbri, Pavel Hulva, Barbora Černá Bolfíková, Milena Jindřichová, Astrid Vik Stronen, Ihor Dykyy, Alessio Camatta, Paolo Carnier, Ettore Randi and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. A legacy of genetic entanglement with wolves shapes modern dogs.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 4 countries.

Romolo CanigliaArea per la Genetica della Conservazione, ISPRA, Ozzano dell'Emilia, Bologna, Italy. romolo.caniglia@isprambiente.it.
Elena FabbriArea per la Genetica della Conservazione, ISPRA, Ozzano dell'Emilia, Bologna, Italy.
Pavel HulvaDepartment of Zoology, Charles University in Prague, Prague, Czech Republic.
Barbora Černá BolfíkováFaculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Prague, Czech Republic.
Milena JindřichováFaculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Prague, Czech Republic.
Astrid Vik StronenDepartment of Chemistry and Bioscience, Aalborg University, Aalborg Øst, Denmark.
Ihor DykyyDepartment of Zoology, Ivan Franko National University of Lviv, Lviv, Ukraine.
Alessio CamattaCLC-Italia, Conegliano, Treviso, Italy.
Paolo CarnierDepartment of Comparative Biomedicine and Food Science, University of Padova, Padova, Italy.
Ettore RandiDipartimento BIGEA, Università di Bologna, Bologna, Italy.
Marco GalaverniArea per la Genetica della Conservazione, ISPRA, Ozzano dell'Emilia, Bologna, Italy.
Aalborg University · DKCzech University of Life Sciences Prague · CZIstituto Superiore per la Protezione e la Ricerca Ambientale · ITAzienda ULSS 9 TREVISO · ITCharles University · CZLviv University · UAUniversity of Padua · ITWWF Italia · IT

Funding

CIGA 20175006Danish Natural Science Research Council 1337-00007IGA CULS 20175018
6 · The paper itself

Abstract

backgroundGenomic methods can provide extraordinary tools to explore the genetic background of wild species and domestic breeds, optimize breeding practices, monitor and limit the spread of recessive diseases, and discourage illegal crossings. In this study we analysed a panel of 170k Single Nucleotide Polymorphisms with a combination of multivariate, Bayesian and outlier gene approaches to examine the genome-wide diversity and inbreeding levels in a recent wolf x dog cross-breed, the Czechoslovakian Wolfdog, which is becoming increasingly popular across Europe.

resultsPairwise F

conclusionsIn this study we successfully applied genome-wide procedures to reconstruct the history of the Czechoslovakian Wolfdog, assess individual wolf ancestry proportions and, thanks to the availability of a well-annotated reference genome, identify possible candidate genes for wolf-like and dog-like phenotypic traits typical of this breed, including commonly inherited disorders. Moreover, through the identification of ancestry-informative markers, these genomic approaches could provide tools for forensic applications to unmask illegal crossings with wolves and uncontrolled trades of recent and undeclared wolfdog hybrids.

Indexed as

GenomeAnimalsBayes TheoremCatechol O-MethyltransferaseCircadian RhythmCzechoslovakiaDNADogsGene OntologyGenetics, PopulationHybridization, GeneticLinkage DisequilibriumLipid MetabolismPolymorphism, Single NucleotidePrincipal Component AnalysisWolvesCatechol O-MethyltransferaseDNAAdmixture historyCzechoslovakian WolfdogDemographic historyGenome ancestryGenome-wide differentiationHybridizationSelection

Identifiers

PMID30005602
PMCPMC6043967
OpenAlexW2884609326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.