Evidence map›Paper›PMID 30005400›Full record

ArticleResearch in veterinary science2018

Long-term shedding of Canine alphaherpesvirus 1 in naturally infected newborn pups.

Michele Losurdo, Giulia Dowgier, Maria Stella Lucente, Mario Cinone, Michele Camero, Maria Loredana Colaianni, Giuseppe Passantino, Gianluca Ventriglia, Domenico Buonavoglia, Nicola Decaro

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In one paragraph

Article in Research in veterinary science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Michele LosurdoDepartment of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
Giulia DowgierDepartment of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy; The Pirbright Institute, Pirbright, Woking, UK.
Maria Stella LucenteDepartment of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
Mario CinoneDepartment of Emergency and Organ Transplantation, University of Bari, Valenzano, Bari, Italy.
Michele CameroDepartment of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
Maria Loredana ColaianniIstituto Zooprofilattico Sperimentale di Puglia e Basilicata, Foggia, Italy.
Giuseppe PassantinoDepartment of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
Gianluca VentrigliaDepartment of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
Domenico BuonavogliaDepartment of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
Nicola DecaroDepartment of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy. Electronic address: nicola.decaro@uniba.it.
University of Bari Aldo Moro · ITIstituto Zooprofilattico Sperimentale della Puglia e della Basilicata · ITThe Pirbright Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long-term shedding of Canine alphaherpesvirus 1 (CaHV-1) by neonatal pups with natural infection is reported. The pups belonged to a litter of 11 pointers of a breeding kennel in southern Italy, 9 of which developed a fatal form of systemic infection, as resulted by the detection of CaHV-1 in internal organs (kidney, liver, lung and brain) of one of this dogs and in the vaginal swab of their mother. The two remaining animals displayed a milder form of disease, with one pup showing ocular involvement, and underwent a progressive recovery. These pups were monitored from 11 to 36  days of age, showing a long-term shedding of the virus through the nasal and ocular secretions and the faeces. CaHV-1 shedding, as assessed by means of a specific and sensitive real-time PCR assay, occurred mainly through the nasal secretions, although the pup displaying ocular disease shed the virus at high titres and for a long period even in the ocular secretions.

Indexed as

Virus SheddingAnimalsAnimals, NewbornDog DiseasesDogsFemaleHerpesviridae InfectionsHerpesvirus 1, CanidItalyReal-Time Polymerase Chain ReactionCanine alphaherpesvirusDogNeonatal infectionViral shedding

Identifiers

PMID30005400
PMCPMC7172181
OpenAlexW2835535804

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.