ArticleThe British journal of radiology2018
High resolution isotropic diffusion imaging in post-mortem neonates: a feasibility study.
Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 7 citations in OpenAlex.
- Quantitative TImaging neuroscience (Cambridge, Mass.) · 2025Article
- Are 3D-printed anatomical models of the ear effective for teaching anatomy? A comparative pilot study versus cadaveric models.Surgical and radiologic anatomy : SRA · 2024Article
- High resolution diffusion imaging in the unfixed post-mortem infant brain at 7T.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Multiparametric mapping in post-mortem perinatal MRI: a feasibility study.The British journal of radiology · 2020Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objective: To investigate the potential of advanced diffusion weighted imaging (DWI) in post-mortem MRI (PMMR) at 3T.
methods: We acquired PMMR brain and body imaging in 12 neonates, mean gestational age 33.4 weeks (range 29-37 weeks) at 3T and 1.5T. Head and body diffusion imaging at 1.5T consisted of bipolar diffusion encoding and single-shot spin-echo echo-planar imaging (SE-EPI) for acquisition (echo time (TE) 96 ms; repetition time (TR) 2700 ms; voxel size 1.8 x 1.8 mm in-plane with slice thickness 5 mm; b-values of 500 and 1000 s/mm
results: There was significant improvement in image quality in multiband, multislice diffusion PMMR protocol. On visual assessment of image quality, 1.5T DWI scored poorly (mean 2.4 SD ± 0.47), and all 3T b-values individually scored significantly higher (p < 0.001) apart from b = 250 s/mm
conclusion: Recent advances in diffusion sequences and hardware utilising higher field strengths and gradient performance allows whole-body diffusion PMMR imaging at high resolution with improved image quality compared to the current clinical approach. ADVANCES IN KNOWLEDGE:: We have demonstrated feasibility of a multislice, multiband quantitative diffusion imaging sequence in the perinatal post-mortem setting. This will allow more detailed and quantitative clinical PMMR investigations using diffusion MRI in the future.
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