Evidence map›Paper›PMID 30004627›Full record

ArticleGenesis (New York, N.Y. : 2000)2018

A mouse model engineered to conditionally express the progesterone receptor-B isoform.

Lan Hai, Maria M Szwarc, Margeaux Wetendorf, San-Pin Wu, Mary C Peavey, Sandra L Grimm, Dean P Edwards, Francesco J DeMayo, John P Lydon

Abstract read
In one paragraph

Article in Genesis (New York, N.Y. : 2000), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Progesterone receptor isoform B regulates theProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Article
  5. Molecular Studies on Pregnancy with Mouse Models.Current opinion in physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Lan HaiDepartment of Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0002-9668-7593
Maria M SzwarcDepartment of Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas.ORCID 0000-0003-2715-2752
Margeaux WetendorfUniversity of North Carolina Chapel Hill, Chapel Hill, North Carolina.
San-Pin WuReproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, Durham, North Carolina.
Mary C PeaveyUNC Fertility, Raleigh, North Carolina.
Sandra L GrimmDepartment of Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas.
Dean P EdwardsDepartment of Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas.
Francesco J DeMayoReproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, Durham, North Carolina.
John P LydonDepartment of Molecular & Cellular Biology, Baylor College of Medicine, Houston, Texas.
Baylor College of Medicine · USNational Institute of Environmental Health Sciences · USRex Hospital · USUniversity of North Carolina at Chapel Hill · US

Funding

Environmental Signaling in Reproduction and PregnancyZIAES103311 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI DEMAYO, FRANCESCO · 2016 to 2025
$30.5M
Molecular Analysis of Uterine ReceptivityR01HD042311 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI LYDON, JOHN P · 2009 to 2023
$4.8M
Molecular Analysis of Uterine ReceptivityU01HD042311 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI DEMAYO, FRANCESCO JOHN · 2002 to 2006
$1.5M
Baylor College of MedicineIntramural NIH HHS Z99 ES999999Intramural NIH HHS ZIA ES103311National Institute of Child Health and Human Development HD-042311NICHD NIH HHS R01 HD042311NICHD NIH HHS U01 HD042311NIH HHS
6 · The paper itself

Abstract

Using a Rosa26 gene targeting strategy in mouse embryonic stem cells, we have generated a new transgenic mouse (Pgr-B

Indexed as

AnimalsCell ProliferationEpithelial CellsEpitheliumFemaleGenetic EngineeringMaleMammary Glands, AnimalMiceMice, TransgenicModels, AnimalMorphogenesisProtein IsoformsReceptors, Progesteroneprogesterone receptor BProtein IsoformsReceptors, Progesteronedifferentiationisoformlactationmammary glandmouseprogesterone receptor-Bproliferationtransgenic

Identifiers

PMID30004627
PMCPMC6141023
OpenAlexW2884885583

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.